The historical development and an overview of contemporary keratoprostheses.

Autor: Moshirfar M; Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA; John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USA; Utah Lions Eye Bank, Murray, UT, USA. Electronic address: Cornea2020@me.com., Moody JJ; Kansas City University College of Osteopathic Medicine, Kansas City, MO, USA., Barke MR; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX., Martheswaran T; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Thomson AC; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX., Thomson RJ; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX., Somani SN; Northwestern Feinberg School of Medicine, Chicago, IL 60611., Shmunes KM; Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA., Ronquillo YC; Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA. Electronic address: yronquillo@hoopesvision.com., Hoopes P; Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA. Electronic address: pch@hoopesvision.com.
Jazyk: angličtina
Zdroj: Survey of ophthalmology [Surv Ophthalmol] 2022 Jul-Aug; Vol. 67 (4), pp. 1175-1199. Date of Electronic Publication: 2022 Jan 23.
DOI: 10.1016/j.survophthal.2022.01.005
Abstrakt: Corneal blindness is a major cause of ocular morbidity that affects 4.5 million people worldwide. Though penetrating keratoplasty is an excellent option for most patients with corneal blindness, there are various conditions for which corneal transplantation carries a low likelihood of success. In cases of multiple failed transplants, the keratoprosthesis, an artificial cornea, is a well-documented surgical option, though few models are commercially available. Keratoprostheses also provide a solution to those in developing areas of the world who do not have access to penetrating keratoplasty owing to limitations in the supply of corneal donor tissue. We summarize the history of keratoprostheses, examine the various keratoprosthesis models used across the globe, and highlight efforts to improve the accessibility and biointegration of keratoprosthesis through novel technological developments.
Competing Interests: Conflict of interest No authors have a conflict of interest related to this work.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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