Rare primary mature teratoma of the liver: A case report.

Autor:	Kovalenko YA; Department of Surgical Oncology and Chemotherapy, A.V. Vishnevsky National Medical Research Center of Surgery of the Russian Ministry of Healthcare, Moscow 115093, Russia., Zharikov YO; Department of Human Anatomy, Sechenov First Moscow State Medical University (Sechenov University), Moscow 119048, Russia. dr_zharikov@mail.ru., Kiseleva YV; International School 'Medicine of the Future', Sechenov First Moscow State Medical University (Sechenov University), Moscow 119048, Russia., Goncharov AB; Department of Surgical Oncology and Chemotherapy, A.V. Vishnevsky National Medical Research Center of Surgery of the Russian Ministry of Healthcare, Moscow 115093, Russia., Shevchenko TV; Department of Surgical Oncology and Chemotherapy, A.V. Vishnevsky National Medical Research Center of Surgery of the Russian Ministry of Healthcare, Moscow 115093, Russia., Gurmikov BN; Department of Surgical Oncology and Chemotherapy, A.V. Vishnevsky National Medical Research Center of Surgery of the Russian Ministry of Healthcare, Moscow 115093, Russia., Kalinin DV; Pathology Department, A.V. Vishnevsky National Medical Research Center of Surgery of the Russian Ministry of Healthcare, Moscow 115093, Russia., Zhao AV; Department of Surgical Oncology and Chemotherapy, A.V. Vishnevsky National Medical Research Center of Surgery of the Russian Ministry of Healthcare, Moscow 115093, Russia.
Jazyk:	angličtina
Zdroj:	World journal of hepatology [World J Hepatol] 2021 Dec 27; Vol. 13 (12), pp. 2192-2200.
DOI:	10.4254/wjh.v13.i12.2192
Abstrakt:	Background: Primary liver teratoma is an extremely rare tumor usually affecting children under the age of 3 years. Specific signs of teratoma on ultrasound, computed tomography (CT) or magnetic resonance imaging are lacking, which makes morphology the only diagnostic tool. Misdiagnosis of a mature teratoma may lead to excessive liver resection, whereas misdiagnosis of an immature teratoma may result in spread, causing a life-threatening condition. Consequently, a careful tumor examination is important, and the rarest types of tumors must be accounted for. Case Summary: We describe a 52 years old female who presented with a solid mass in the left liver lobe. Contrast-enhanced CT and magnetic resonance imaging (MRI) revealed a round, heterogeneous lesion containing a number of fluid areas and areas of calcification in the middle, and the provisional diagnosis was cholangiocarcinoma. The patient underwent resection of liver segment I. Immunohistochemistry analysis of the resected lesion indicated thyroid follicular epithelium; however, the thyroid gland was intact. 10 years prior to presentation the patient underwent a surgery due to mature teratoma of the right ovary, nevertheless the tumor was benign and could not spread to the liver, in addition teratoma of the liver was also benign. This led to the final diagnosis of primary mature liver teratoma. Conclusion: Primary hepatic teratoma, including heterotopia of the thyroid gland in the liver, is an extremely rare condition in adults that needs to be considered in the differential diagnosis of solid-cystic neoplasms in the liver and cholangiocarcinoma. This case adds to the limited literature on the patient presentation, clinical workup and management of liver teratomas. Competing Interests: Conflict-of-interest statement: The authors declare that they have no conflicts of interest. (©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze:	MEDLINE
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