Personalized approach in arrhythmology by genetic-based data: a case report.

Autor: Blokhina AV; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Ershova AI; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Zyatenkova EV; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Meshkov AN; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Kiseleva AV; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Klimushina MV; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Sotnikova EA; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Skirko OP; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Zharikova AA; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia.; Faculty of Bioengineering & Bioinformatics, Leninskie Gory, 1-73, Moscow, 119991, Russia., Doludin YV; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Kharlap MS; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia., Drapkina OM; National Medical Research Center for Therapy & Preventive Medicine, Petroverigsky lane, 10/3, Moscow, 101990, Russia.
Jazyk: angličtina
Zdroj: Personalized medicine [Per Med] 2022 Mar; Vol. 19 (2), pp. 83-91. Date of Electronic Publication: 2022 Jan 21.
DOI: 10.2217/pme-2021-0090
Abstrakt: The results of molecular genetic testing may affect recommended treatment or therapeutic decisions and risk assessment, may help with identification of family members at risk. Here, we report a case of a young patient with a paradoxical combination of two inherited arrhythmic syndromes and demonstrate the role of genetic testing as one of the basis of personalized approach in diagnosis, treatment and prevention complications of inherited channelopathies complications. Integration of genetic testing results into clinical practice is a successful example of the concept of personalized medicine.
Databáze: MEDLINE
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