Clinical differentiation of inflammatory bowel disease (IBD) in Latin America and the Caribbean.

Autor:	Yamamoto-Furusho JK; Inflammatory Bowel Disease Clinic, Gastroenterology Department, National Institute of Medical Science and Nutrition Salvador Zubirán, Mexico City, Mexico., Parra-Holguín NN; Inflammatory Bowel Disease Clinic, Gastroenterology Department, National Institute of Medical Science and Nutrition Salvador Zubirán, Mexico City, Mexico., Juliao-Baños F; Hospital Pablo Tobón Uribe, Medellín, Colombia., Puentes F; United Surgeons, Manizales, Colombia., López R; Santa Fe Foundation, Bogotá, Colombia., Bosques-Padilla F; Department of Gastroenterology, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico., Torres EA; University of Puerto Rico, San Juan, Puerto Rico., Nieves-Jimenéz H; University of Puerto Rico, San Juan, Puerto Rico., Veitia-Velásquez GR; Gastroenterology Service, Hospital Vargas de Caracas, Caracas, Venezuela., Jara-Alba ML; Hospital Dr. Teodoro Maldonado Carbo - Instituto Ecuatoriano de Seguridad Social (IESS), Guayaquil, Ecuador., Bautista S; Centros de Diagnóstico y Medicina Avanzada y de Conferencias Médicas y Telemedicina (CEDIMAT) Gastroenterology Center, Santo Domingo, Dominican Republic., Piñol-Jimenez FN; National Center for Minimally Access Surgery, Habana, Cuba., Salgado-Rosado P; Hospital Dr. Teodoro Maldonado Carbo - Instituto Ecuatoriano de Seguridad Social (IESS), Guayaquil, Ecuador., Villa-Ovalles KC; Centros de Diagnóstico y Medicina Avanzada y de Conferencias Médicas y Telemedicina (CEDIMAT) Gastroenterology Center, Santo Domingo, Dominican Republic., Abreu-Martinez YA; Regional University Hospital José María Cabral y Baez, Santiago de los Caballeros, Dominican Republic., Borges Z; Regional University Hospital José María Cabral y Baez, Santiago de los Caballeros, Dominican Republic., Davila-Bedoya S; Hospital Carlos Andrade Marin, Quito, Ecuador., Otoya-Moreno G; Private Practice, Lima, Perú., Iadé-Vergara B; Centro de Asistencia del Sindicato Médico del Uruguay (CASMU) Cooperativa de Servicios Médicos (COSEM), Uruguay.
Jazyk:	angličtina
Zdroj:	Medicine [Medicine (Baltimore)] 2022 Jan 21; Vol. 101 (3), pp. e28624.
DOI:	10.1097/MD.0000000000028624
Abstrakt:	Abstract: The aim of the present study was to describe the epidemiological and clinical characteristics of inflammatory bowel disease (IBD), including medical and surgical treatments, in several countries in Latin America and the Caribbean.IBD is recognized as a global health problem because its incidence and prevalence have increased significantly over the last few years.This multicenter retrospective cohort study included 4714 patients with IBD diagnosed from 9 countries in Latin America and the Caribbean: Colombia, Cuba, Dominican Republic, Ecuador, Mexico, Peru, Puerto Rico, Uruguay, and Venezuela.Crohn disease (CD) was more frequent in Puerto Rico (71.9%), the Dominican Republic (61.0%), and Peru (53.1%). Ulcerative colitis was more frequent in Colombia (78.6%), Venezuela (78.2%), Mexico (75.5%), Cuba (69.9%), Ecuador (64.1%), and Uruguay (60.9%). The following clinical characteristics were more frequent in the Caribbean: penetrating behavior in CD, steroid dependence, steroid resistance, intolerance to thiopurines, extraintestinal manifestations, surgeries, hospitalizations due to IBD, and family history of IBD. The factors associated with the use of biological therapy were pancolitis in ulcerative colitis, penetrating behavior in CD, steroid resistance and dependence, presence of extraintestinal manifestations, and the need for surgery.This study from Latin America and the Caribbean demonstrated the different epidemiological and clinical characteristics of IBD. Competing Interests: The authors have no conflicts of interest to disclose. (Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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