| Autor: |
Huesca-Urióstegui K; Tecnológico de Monterrey, Centro de Biotecnologia-FEMSA., Av. Eugenio Garza Sada 2501 Sur, Monterrey 64849, NL, Mexico., García-Valderrama EJ; Tecnológico de Monterrey, Centro de Biotecnologia-FEMSA., Av. Eugenio Garza Sada 2501 Sur, Monterrey 64849, NL, Mexico., Gutierrez-Uribe JA; Tecnológico de Monterrey, Centro de Biotecnologia-FEMSA., Av. Eugenio Garza Sada 2501 Sur, Monterrey 64849, NL, Mexico., Antunes-Ricardo M; Tecnológico de Monterrey, Centro de Biotecnologia-FEMSA., Av. Eugenio Garza Sada 2501 Sur, Monterrey 64849, NL, Mexico., Guajardo-Flores D; Tecnológico de Monterrey, Centro de Biotecnologia-FEMSA., Av. Eugenio Garza Sada 2501 Sur, Monterrey 64849, NL, Mexico. |
| Jazyk: |
angličtina |
| Zdroj: |
Pharmaceutics [Pharmaceutics] 2022 Jan 14; Vol. 14 (1). Date of Electronic Publication: 2022 Jan 14. |
| DOI: |
10.3390/pharmaceutics14010191 |
| Abstrakt: |
Nanofibers have emerged as a potential novel platform due to their physicochemical properties for healthcare applications. Nanofibers' advantages rely on their high specific surface-area-to-volume and highly porous mesh. Their peculiar assembly allows cell accommodation, nutrient infiltration, gas exchange, waste excretion, high drug release rate, and stable structure. This review provided comprehensive information on the design and development of natural-based polymer nanofibers with the incorporation of herbal medicines for the treatment of common diseases and their in vivo studies. Natural and synthetic polymers have been widely used for the fabrication of nanofibers capable of mimicking extracellular matrix structure. Among them, natural polymers are preferred because of their biocompatibility, biodegradability, and similarity with extracellular matrix proteins. Herbal bioactive compounds from natural extracts have raised special interest due to their prominent beneficial properties in healthcare. Nanofiber properties allow these systems to serve as bioactive compound carriers to generate functional matrices with antimicrobial, anti-inflammatory, antioxidant, antiseptic, anti-viral, and other properties which have been studied in vitro and in vivo, mostly to prove their wound healing capacity and anti-inflammation properties. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
