| Autor: |
Olariu TR; Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.; Clinical Laboratory, Municipal Clinical Emergency Teaching Hospital, 300254 Timisoara, Romania.; Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania., Craciun AC; Clinical Laboratory, Municipal Clinical Emergency Teaching Hospital, 300254 Timisoara, Romania., Vlad DC; Department of Biochemistry and Pharmacology, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.; Clinical Laboratory, County Clinical Emergency Teaching Hospital, 300723 Timisoara, Romania., Dumitrascu V; Department of Biochemistry and Pharmacology, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.; Clinical Laboratory, County Clinical Emergency Teaching Hospital, 300723 Timisoara, Romania., Marincu I; Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania., Lupu MA; Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.; Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.; Clinical Laboratory, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania. |
| Abstrakt: |
Background and Objectives: The extent of SARS-CoV-2 infection among a population may be assessed by the presence of serum SARS-CoV-2 antibodies, which indicates previous exposure. The aim of this study was to determine the seroprevalence of SARS-CoV-2 infection in the adult population from Western Romania. Materials and Methods: Samples of 2443 consecutive individuals, referred for routine laboratory investigations, were tested for SARS-CoV-2 antibodies using the Elecsys immunoassay that targets the nucleocapsid protein, for identifying the presence of the total antibodies against SARS-CoV-2. Results: The overall SARS-CoV-2 seroprevalence was 45.60%. SARS-CoV-2 seroprevalence was significantly higher in age group 30-49 years (53.94%) compared to age groups 50-69 years (43.53%) and 70-91 years (30.79%) ( p < 0.001, p < 0.001, respectively). No significant difference in seroprevalence was observed between females (44.83%) and males (47.05%). Conclusions: Our data revealed a high seroprevalence of SARS-CoV-2 infection in the adult population from Western Romania and indicate the rapid and significant spread of the virus. The estimated prevalence of 45.60% was 6 times higher than the rate of confirmed COVID-19 cases reported in the study area. This indicates the magnitude of virus transmission in the community. |
