Differential Diagnosis of Hepatic Mass with Central Scar: Focal Nodular Hyperplasia Mimicking Fibrolamellar Hepatocellular Carcinoma.

Autor: Rudolphi-Solero T; Nuclear Medicine Department, Virgen de las Nieves Hospital, 18014 Granada, Spain., Triviño-Ibáñez EM; Nuclear Medicine Department, Virgen de las Nieves Hospital, 18014 Granada, Spain., Medina-Benítez A; Radiology Department, Virgen de las Nieves Hospital, 18014 Granada, Spain., Fernández-Fernández J; Nuclear Medicine Department, Virgen de las Nieves Hospital, 18014 Granada, Spain., Rivas-Navas DJ; Nuclear Medicine Department, Virgen de las Nieves Hospital, 18014 Granada, Spain., Pérez-Alonso AJ; Surgery Department, Virgen de las Nieves Hospital, 18014 Granada, Spain., Gómez-Río M; Nuclear Medicine Department, Virgen de las Nieves Hospital, 18014 Granada, Spain., Aroui-Luquin T; Nuclear Medicine Department, Virgen de las Nieves Hospital, 18014 Granada, Spain., Rodríguez-Fernández A; Nuclear Medicine Department, Virgen de las Nieves Hospital, 18014 Granada, Spain.
Jazyk: angličtina
Zdroj: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2021 Dec 27; Vol. 12 (1). Date of Electronic Publication: 2021 Dec 27.
DOI: 10.3390/diagnostics12010044
Abstrakt: Fibrolamellar hepatocellular carcinoma is a primary hepatic tumor that usually appears in young adults. Radical surgery is considered curative for this kind of tumor, so early diagnosis becomes essential for the prognosis of the patients. The main characteristic of this entity is the central scar, which is the center of differential diagnosis. We report the case of a 30-year-old man who was diagnosed with fibrolamellar hepatocellular carcinoma by ultrasonography. Contrast-enhanced CT confirmed this diagnosis, and the patient underwent a [ 18 F] fluorocholine PET/CT. Hypermetabolism and the morphology in the nuclear medicine exploration suggest neoplastic nature of the lesion. Radical surgery was performed, and histopathologic analysis was performed, which resulted in focal nodular hyperplasia. Hepatic masses with central scar could have a difficult differential diagnosis, and focal nodular hyperplasia could mimic fibrolamellar hepatocellular carcinoma imaging patterns. These morphofunctional characteristics have not been described in [ 18 F] Fluorocholine PET/CT, so there is a need to find out the potential role PET/CT in the differential diagnosis of hepatic mass with central scar.
Databáze: MEDLINE
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