| Autor: |
Pescariu SA; Department VI, Discipline of Cardiology, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; Cardiology Clinic, Institute of Cardiovascular Medicine Timişoara, 13A, Gheorghe Adam Street, 300310 Timisoara, Romania.; Research Center for Cardiovascular Diseases, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania.; Doctoral School, 'Victor Babes' University of Medicine and Pharmacy Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania., Şoşdean R; Department VI, Discipline of Cardiology, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; Cardiology Clinic, Institute of Cardiovascular Medicine Timişoara, 13A, Gheorghe Adam Street, 300310 Timisoara, Romania.; Research Center for Cardiovascular Diseases, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania., Tudoran C; Department VII, Internal Medicine II, Discipline of Cardiology, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; Center of Molecular Research in Nephrology and Vascular Disease, Faculty of Medicine, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; County Emergency Hospital, L. Rebreanu Str., Nr. 156, 300723 Timisoara, Romania., Ionac A; Department VI, Discipline of Cardiology, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; Cardiology Clinic, Institute of Cardiovascular Medicine Timişoara, 13A, Gheorghe Adam Street, 300310 Timisoara, Romania.; Research Center for Cardiovascular Diseases, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania., Pop GN; Department VI, Discipline of Cardiology, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania., Timar RZ; Department VII, Internal Medicine II, Discipline of Cardiology, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; Center of Molecular Research in Nephrology and Vascular Disease, Faculty of Medicine, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; County Emergency Hospital, L. Rebreanu Str., Nr. 156, 300723 Timisoara, Romania., Pescariu S; Department VI, Discipline of Cardiology, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; Cardiology Clinic, Institute of Cardiovascular Medicine Timişoara, 13A, Gheorghe Adam Street, 300310 Timisoara, Romania.; Research Center for Cardiovascular Diseases, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania., Tudoran M; Department VII, Internal Medicine II, Discipline of Cardiology, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; Center of Molecular Research in Nephrology and Vascular Disease, Faculty of Medicine, University of Medicine and Pharmacy 'Victor Babes' Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.; County Emergency Hospital, L. Rebreanu Str., Nr. 156, 300723 Timisoara, Romania. |
| Abstrakt: |
Cardiac resynchronization therapy (CRT) represents an increasingly recommended solution to alleviate symptomatology and improve the quality of life in individuals with dilated cardiomyopathy (DCM) and heart failure (HF) with reduced ejection fraction (HFrEF) who remain symptomatic despite optimal medical therapy (OMT). However, this therapy does have the desired results all cases, in that sometimes low sensing and high voltage stimulation are needed to obtain some degree of resynchronization, even in the case of perfectly placed cardiac pacing leads. Our study aims to identify whether there is a relationship between several transthoracic echocardiographic (TTE) parameters characterizing left ventricular (LV) performance, especially strain results, and sensing and pacing parameters. Between 2020-2021, CRT was performed to treat persistent symptoms in 48 patients with a mean age of 64 (53.25-70) years, who were diagnosed with DCM and HFrEF, and who were still symptomatic despite OMT. We documented statistically significant correlations between global longitudinal strain, posterolateral strain, and ejection fraction and LV sensing (r = 0.65, 0.469, and 0.534, respectively, p < 0.001) and LV pacing parameters (r = -0.567, -0.555, and -0.363, respectively, p < 0.001). Modern imaging techniques, such as TTE with cardiac strain, are contributing to the evaluation of patients with HFrEF, increasing the chances of CRT success, and allowing physicians to anticipate and plan for case management. |
