Smart Bioinks for the Printing of Human Tissue Models.

Autor: Maan Z; Department of Mechanical Engineering, University of Ottawa, Ottawa, ON K1S 5J6, Canada., Masri NZ; Division of Medical Sciences, University of Victoria, Victoria, BC V8W 2Y2, Canada., Willerth SM; Division of Medical Sciences, University of Victoria, Victoria, BC V8W 2Y2, Canada.; Department of Mechanical Engineering, University of Victoria, Victoria, BC V8W 2Y2, Canada.; Centre for Advanced Materials and Technology, University of Victoria, Victoria, BC V8W 2Y2, Canada.; School of Biomedical Engineering, University of British Columbia, Victoria, BC V6T 1Z4, Canada.
Jazyk: angličtina
Zdroj: Biomolecules [Biomolecules] 2022 Jan 15; Vol. 12 (1). Date of Electronic Publication: 2022 Jan 15.
DOI: 10.3390/biom12010141
Abstrakt: 3D bioprinting has tremendous potential to revolutionize the field of regenerative medicine by automating the process of tissue engineering. A significant number of new and advanced bioprinting technologies have been developed in recent years, enabling the generation of increasingly accurate models of human tissues both in the healthy and diseased state. Accordingly, this technology has generated a demand for smart bioinks that can enable the rapid and efficient generation of human bioprinted tissues that accurately recapitulate the properties of the same tissue found in vivo. Here, we define smart bioinks as those that provide controlled release of factors in response to stimuli or combine multiple materials to yield novel properties for the bioprinting of human tissues. This perspective piece reviews the existing literature and examines the potential for the incorporation of micro and nanotechnologies into bioinks to enhance their properties. It also discusses avenues for future work in this cutting-edge field.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje