| Autor: |
Teixeira SA; Hospital Geral de Fortaleza - HGF, Fortaleza, Ceará, Brazil., Moreira JLS; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Sousa NRT; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Pereira AMC; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Rodrigues PN; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Santos ASD; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Andrade AMLC; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Rolim Neto ML; Juazeiro do Norte School of Medicine from Juazeiro do Norte - FMJ/Estacio, Juazeiro do Norte, Ceará, Brazil., Araújo JEB; School of Medicine, Federal University of Campina Grande - UFCG, Cajazeiras, Paraíba, Brasil., Machado SSF; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Vieira NB; School of Medicine, Federal University of Cariri - UFCA, Barbalha, Ceará, Brazil., Lima DGS; Juazeiro do Norte School of Medicine from Juazeiro do Norte - FMJ/Estacio, Juazeiro do Norte, Ceará, Brazil., Filho FHP; School of Medicine - Universidad Central del Paraguay - Sede 2 - Asunción, Paraguay. |
| Abstrakt: |
It is possible to consider the stimulation of the cingulate gyrus in its portion below the corpus callosum (SCC, or subcallosal cingulate cortex) as an effective, promising, and safe alternative intervention for treatment-resistant depression. In studies with deep brain stimulation - DBS, when follow-on with functional magnetic resonance imaging and/or PET-CT (Positron emission tomography-computed tomography) is performed, it is observed an increase in the blood supply and glucose metabolism in this region, which is the anterior part of the limbic system. This same location has good experimental results also for the treatment of anorexia nervosa. The hypotheses suggest a greater activation of the reward system, a greater sense of well-being, and a consequent reduction in depressive symptoms, the objective of the treatment. Over the last 20 years, multicenter studies have shown symptomatic improvement in 50-60% of patients, and about a third even reach criteria for remission of the depressive disorder. |
