| Autor: |
Babu SS; Department of Chemistry, Indian Institute of Science Education and Research (IISER) Tirupati, Tirupati 517507, India. gopi@iisertirupati.ac.in., Varma AA; Department of Chemistry, Indian Institute of Science Education and Research (IISER) Tirupati, Tirupati 517507, India. gopi@iisertirupati.ac.in., Gopinath P; Department of Chemistry, Indian Institute of Science Education and Research (IISER) Tirupati, Tirupati 517507, India. gopi@iisertirupati.ac.in. |
| Jazyk: |
angličtina |
| Zdroj: |
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2022 Feb 08; Vol. 58 (12), pp. 1990-1993. Date of Electronic Publication: 2022 Feb 08. |
| DOI: |
10.1039/d1cc06289a |
| Abstrakt: |
Herein, we report a substrate-controlled cascade cyclization of o -alkenyl aryl ureas, an ambident nucleophile for constructing functionalized heterocycles such as 2-amino-1,3-benzoxazines and dihydroquinazolinones in a chemodivergent fashion using photoredox catalysis under mild conditions. The versatility of the method has been successfully demonstrated by applying this strategy to a wide range of substrates and for the synthesis of functionalized etifoxine drug derivatives. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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