Impact of marital status on survival in patients with stage 1A NSCLC.

Autor:	Huang L; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P.R. China., Peng S; Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P.R. China., Sun C; AMITA Health Saint Joseph Hospital Chicago, Chicago, IL 60657, USA., Chen L; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P.R. China., Chu Q; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P.R. China., Thapa S; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P.R. China., Chummun V; Department of Radiotherapy and Oncology, Victoria Hospital, Candos, Quatre Bornes 72259, Mauritius., Zhang L; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P.R. China., Zhang P; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P.R. China., Chen EL; AMITA Health Saint Joseph Hospital Chicago, Chicago, IL 60657, USA., Cheng C; The University of Arizona College of Medicine at South Campus, Tucson, AZ 85713, USA., Chen Y; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, P.R. China.
Jazyk:	angličtina
Zdroj:	Aging [Aging (Albany NY)] 2022 Jan 19; Vol. 14 (2), pp. 770-779. Date of Electronic Publication: 2022 Jan 19.
DOI:	10.18632/aging.203838
Abstrakt:	Objectives: To study how marital status influences overall survival (OS) in patients with stage IA non-small cell lung cancer (NSCLC). And whether the result is valid in different time periods. Materials and Methods: We retrospectively analyzed 55,207 cases of stage IA NSCLC from 1995 to 2015 in the Surveillance, Epidemiology, and End Results (SEER) database. Marital status was classified as follows: married or with unmarried/domestic partner (MR/W.P), divorced or separated (DV/SP), widowed (WD), and single (never married). Patients diagnosed in 1995-2005 and 2006-2015 were analyzed separately as groups 1 and 2, respectively, to validate the results. Within each group, age-stratified demographic, clinicopathologic features, and OS were compared among different marital statuses. Results and Conclusions: A total of 55,207 cases were included (group 1 n=20,223, group 2 n=34,984). From 1995-2005 to 2006-2015, median OS was prolonged significantly in all patients besides the DV/SP subgroup. In general, being MR/W.P was associated with the lowest relative risk of death in the study population (Group 1, HR= 0.854, 95%CI: 0.816-0.893; Group 2, HR = 0.799, 95%CI: 0.758-0.842). Meanwhile, OS of DV/SP and widowed patients was similar. In group 2, being single was associated with lower risk of death beyond 60-year-old.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu