[Some psychiatric and neurological aspects of the asymptomatic and mild course of COVID-19].

Autor:	Chritinin DF; Kirov Military Medical Academy, St-Petersburg, Russia., Shamrey VK; Kirov Military Medical Academy, St-Petersburg, Russia., Kurasov ES; Kirov Military Medical Academy, St-Petersburg, Russia., Litvinenko IV; Kirov Military Medical Academy, St-Petersburg, Russia., Tsygan NV; Kirov Military Medical Academy, St-Petersburg, Russia.; Konstantinov Petersburg Institute of Nuclear Physics of the National Research Center «Kurchatov Institute», Gatchina, Russia.; National Research Center «Kurchatov Institute», Moscow, Russia., Golokhvastov SY; Kirov Military Medical Academy, St-Petersburg, Russia., Ryabtsev AV; Kirov Military Medical Academy, St-Petersburg, Russia.; Konstantinov Petersburg Institute of Nuclear Physics of the National Research Center «Kurchatov Institute», Gatchina, Russia.; National Research Center «Kurchatov Institute», Moscow, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2021; Vol. 121 (12), pp. 13-18.
DOI:	10.17116/jnevro202112112113
Abstrakt:	Objective: To study neurological and mental disorders associated with the inapparent and mild course of COVID-19. Material and Methods: The study included 50 patients (mean age 35.2±11.4 years) admitted to a psychiatric hospital due to depressive spectrum disorders. Patients were divided into two groups: patients ( n =16) who had IgG antibodies to SARS-CoV-2 (main group) and patients ( n =34) without a history of COVID-19 (comparison group). Results and Conclusion: Patients of the main group showed a difference in the structure of asthenic disorders compared with the comparison group. Also, there was a significant predominance of the severity of asthenic symptoms and anxiety in the structure of psychopathological disorders in depressive spectrum disorders. The viral intoxication contributes to the formation of a kind of asthenic «soil» (with characteristic manifestations). In the future, in the case of the development of any stress-associated disorder, more pronounced psychopathological disorders are noted compared with patients of the comparison group. The authors describe a variant of the course of COVID-19, in which the development of ischemic stroke was the first clinical manifestation of the disease. These disorders are based on the pronounced neurotropic effect of SARS-CoV-2 and its effect on the neurovascular unit.
Databáze:	MEDLINE
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