Viral co-pathogens in COVID-19 acute respiratory syndrome - what did we learn from the first year of pandemic?

Autor:	Kriger O; Sheba Medical Center, Ramat-Gan, Israel. Electronic address: or.kriger@sheba.health.gov.il., Gefen-Halevi S; Sheba Medical Center, Ramat-Gan, Israel., Leshem E; Sheba Medical Center, Ramat-Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Smollan G; Sheba Medical Center, Ramat-Gan, Israel., Belausov N; Sheba Medical Center, Ramat-Gan, Israel., Egbarye A; Sheba Medical Center, Ramat-Gan, Israel., Khashab R; Sheba Medical Center, Ramat-Gan, Israel., Odeh M; Sheba Medical Center, Ramat-Gan, Israel., Saffia A; Sheba Medical Center, Ramat-Gan, Israel., Barak Y; Sheba Medical Center, Ramat-Gan, Israel., Hussein OA; Sheba Medical Center, Ramat-Gan, Israel., Hamias R; Sheba Medical Center, Ramat-Gan, Israel., Aharon Y; Sheba Medical Center, Ramat-Gan, Israel., Alfandari J; Sheba Medical Center, Ramat-Gan, Israel., Nemet I; Central Virology Laboratory, Ministry of Health, Ramat-Gan, Israel., Kliker L; Central Virology Laboratory, Ministry of Health, Ramat-Gan, Israel., Sherbany H; Central Virology Laboratory, Ministry of Health, Ramat-Gan, Israel., Mandelboim M; Central Virology Laboratory, Ministry of Health, Ramat-Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Amit S; Sheba Medical Center, Ramat-Gan, Israel.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2022 Mar; Vol. 116, pp. 226-229. Date of Electronic Publication: 2022 Jan 14.
DOI:	10.1016/j.ijid.2022.01.018
Abstrakt:	Objective: This study aimed to describe the distribution of respiratory pathogens and the occurrence of co-pathogens during the first year of the COVID-19 pandemic. Methods: We used a multiplex polymerase chain reaction (PCR) panel targeting 23 microorganisms to analyze the oro-pharyngeal samples of patients admitted to our hospital with acute respiratory infection (ARI) between March 1, 2020, and February 28, 2021. We matched 40 to 50 patients who were SARS-CoV-2 positive and SARS-CoV-2 negative per month for age and sex. Results: A total of 939 patients with multiplex PCR test results were included in the study. Respiratory pathogens where detected in only 8/476 (1.6%) patients with COVID-19 versus 87/463 (18.7%) patients with non-COVID-19 ARI patients. Diversity and rates of pathogens vastly differed from previous years but showed seasonal variance. Conclusion: Patients with SARS-CoV-2 infection presenting with ARI during the first year of the COVID-19 pandemic demonstrated paucity of respiratory co-pathogens. (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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