A case of long-term complete remission of locally advanced T4 bladder cancer treated with pembrolizumab.

Autor:	Horibe Y; Departments of Urology, Osaka Rosai Hospital, 1179-3 Nagasone, Kitaku, Sakai City, Osaka, 591-8025, Japan., Nakata W; Departments of Urology, Osaka Rosai Hospital, 1179-3 Nagasone, Kitaku, Sakai City, Osaka, 591-8025, Japan., Tsujimura G; Departments of Urology, Osaka Rosai Hospital, 1179-3 Nagasone, Kitaku, Sakai City, Osaka, 591-8025, Japan., Tsujimoto Y; Departments of Urology, Osaka Rosai Hospital, 1179-3 Nagasone, Kitaku, Sakai City, Osaka, 591-8025, Japan., Gotoh T; Departments of Pathology, Osaka Rosai Hospital, 1179-3 Nagasone, Kitaku, Sakai City, Osaka, 591-8025, Japan., Tsujihata M; Departments of Urology, Osaka Rosai Hospital, 1179-3 Nagasone, Kitaku, Sakai City, Osaka, 591-8025, Japan.
Jazyk:	angličtina
Zdroj:	Urology case reports [Urol Case Rep] 2021 Nov 27; Vol. 41, pp. 101959. Date of Electronic Publication: 2021 Nov 27 (Print Publication: 2022).
DOI:	10.1016/j.eucr.2021.101959
Abstrakt:	A 69-year-old man with a history of non-muscle invasive bladder cancer 12 years ago presented complaining of gross hematuria. He was diagnosed as having invasive T4 bladder cancer with invasion to a branch of the internal iliac artery and received platinum-based chemo-radiation therapy. However, the tumor progressed to extensively infiltrate the pelvic wall, and left leg pain and swelling developed. Pembrolizumab was started, which entirely resolved the tumor after 14 courses of treatment. Pembrolizumab was discontinued after 20 courses of treatment because of adverse events. However, the patient has remained in complete response for over 2 years after pembrolizumab cessation. (© 2021 The Authors.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu