Obscure Gastrointestinal Bleeding Due to Non-steroidal Anti-inflammatory Drug-Induced Colopathy.

Autor: Meshikhes HA; Medicine, Immam Abdulrahman Bin Faisal University, Dammam, SAU., Duhaileb MA; Surgery, King Fahad Specialist Hospital, Dammam, SAU., Alzahir AA; Surgery, King Fahad Specialist Hospital, Dammam, SAU., Almomen SA; Gastroenterology and Hepatology, King Fahad Specialist Hospital, Dammam, SAU., Meshikhes AN; Surgery, Alzahra General Hospital, Qatif, SAU.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2021 Dec 08; Vol. 13 (12), pp. e20278. Date of Electronic Publication: 2021 Dec 08 (Print Publication: 2021).
DOI: 10.7759/cureus.20278
Abstrakt: Obscure gastrointestinal (GI) bleeding poses a diagnostic challenge and is associated with high mortality. We report a case of life-threatening obscure GI bleeding precipitated by the ingestion of a non-steroidal anti-inflammatory drug (NSAID). The source of bleeding could not be identified preoperatively, and hence exploratory laparotomy was performed. An ileocaecal resection was undertaken based on the findings of the intraoperative enteroscopy. However, the bleeding recurred and repeated endoscopy examination identified the source to be multiple NSAID-induced ulcers that were scattered in the colo-rectum. The bleeding stopped spontaneously after a period of intensive supportive therapy and sulphasalazine enemas. This case highlights the diagnostic challenge of obscure GI bleeding. It also highlights the potentially life-threatening danger of GI bleeding secondary to NSAID-induced colopathy, even after a short course of treatment.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2021, Meshikhes et al.)
Databáze: MEDLINE