Onychomycosis: experience of the laboratory of parasitology-mycology of CHU-Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar.

Autor: Zafindraibe NJ; Paraclinic Unit of Formation and Research (UPFR), Parasitology - Mycology, CHU Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar.; Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar., Tsatoromila FAM; Regional Center for Blood Transfusion Analamanga, Antananarivo, Madagascar., Rakotoarivelo ZH; Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar., Rakotozandrindrainy N; Paraclinic Unit of Formation and Research (UPFR), Parasitology - Mycology, CHU Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar., Rafalimanana C; Paraclinic Unit of Formation and Research (UPFR), Parasitology - Mycology, CHU Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar., Rakoto-Alson OA; Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar., Razanakolona LR; Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar.; National Reference Laboratory (NRL) for HIV/AIDS and Sexually Transmitted Infections, Antananarivo, Madagascar.
Jazyk: angličtina
Zdroj: The Pan African medical journal [Pan Afr Med J] 2021 Nov 22; Vol. 40, pp. 176. Date of Electronic Publication: 2021 Nov 22 (Print Publication: 2021).
DOI: 10.11604/pamj.2021.40.176.25216
Abstrakt: Introduction: onychomycosis is defined as a fungal infection of the nails. They represent the main cause of onychopathy. They constitute a public health problem because of their increased prevalence in the world ranging between 20 to 30%. However, they remain under documented in Madagascar. This study was conducted in order to determine the mycological profile of onychomycosis diagnosed in the Parasitology Mycology laboratory of CHU-JRA.
Methods: a descriptive retrospective study was taken over a 13-year period from June 2005 to December 2018. The data presenting onychomycosis on the mycological outcome register were included in the study. Results showing the presence of fungi on direct examination and / or culture were considered positive.
Results: during the study period, a prevalence of 17.75% (180/1014) was observed. The age of our patients ranged from 3 to 76 years. Women were the most affected in 68.34% (n = 123) with a sex ratio of 0.46. Onychomycosis was localized in 64.65% of the fingers (n = 128). Simultaneous involvement of the hands and feet was found in 10% of the cases (n = 18). Candida albicans (C. albicans) was the most isolated in 33.03% (n = 71) of cases, followed by other species of Candida (24.65%, n = 53) and Trichophyton spp (9.3%, n=17). Mixed infections associating dermatophytes, Yeasts and molds were found in 23.33% (n = 42) of the cases.
Conclusion: this is the first investigation dealing with onychomycosis in Madagascar. These data may be useful for future research and in the development of preventive and educational strategies.
Competing Interests: The authors declare no competing interests.
(Copyright: Norosoa Julie Zafindraibe et al.)
Databáze: MEDLINE
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