| Autor: |
Vedernikov YP; All-Union Cardiology Research Centre, U.S.S.R. Academy of Medical Sciences, Moscow., Vihert AM, Leisner H |
| Jazyk: |
angličtina |
| Zdroj: |
European journal of pharmacology [Eur J Pharmacol] 1987 Oct 27; Vol. 142 (3), pp. 471-4. |
| DOI: |
10.1016/0014-2999(87)90091-4 |
| Abstrakt: |
10(-6) M EDRF released from perfused arterial donor segments in a superfusion bioassay system, either spontaneously or stimulated by acetylcholine, did not inhibit the contractility of electrically stimulated right ventricle papillary muscle of pig, rabbit and rat. EDRF also did not inhibit spontaneously contracting rat portal vein and thus relaxed precontracted arterial rings denuded of endothelium. The results suggest that EDRF released by arterial endothelial cells is a local modulator of arterial smooth muscle and is not important for extraarterial tissue regulation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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