Short-Term Joint Effects of PM 10 , NO 2 and SO 2 on Cardio-Respiratory Disease Hospital Admissions in Cape Town, South Africa.

Autor: Adebayo-Ojo TC; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Kreuzstrasse 2, 4123 Allschwil, Switzerland.; Faculty of Medicine, University of Basel, 4056 Basel, Switzerland., Wichmann J; Faculty of Health Sciences, School of Health Systems and Public Health, University of Pretoria, Pretoria 0002, South Africa., Arowosegbe OO; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Kreuzstrasse 2, 4123 Allschwil, Switzerland.; Faculty of Medicine, University of Basel, 4056 Basel, Switzerland., Probst-Hensch N; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Kreuzstrasse 2, 4123 Allschwil, Switzerland.; Faculty of Medicine, University of Basel, 4056 Basel, Switzerland., Schindler C; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Kreuzstrasse 2, 4123 Allschwil, Switzerland.; Faculty of Medicine, University of Basel, 4056 Basel, Switzerland., Künzli N; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Kreuzstrasse 2, 4123 Allschwil, Switzerland.; Faculty of Medicine, University of Basel, 4056 Basel, Switzerland.
Jazyk: angličtina
Zdroj: International journal of environmental research and public health [Int J Environ Res Public Health] 2022 Jan 03; Vol. 19 (1). Date of Electronic Publication: 2022 Jan 03.
DOI: 10.3390/ijerph19010495
Abstrakt: Background/aim: In sub-Sahara Africa, few studies have investigated the short-term association between hospital admissions and ambient air pollution. Therefore, this study explored the association between multiple air pollutants and hospital admissions in Cape Town, South Africa.
Methods: Generalized additive quasi-Poisson models were used within a distributed lag linear modelling framework to estimate the cumulative effects of PM 10 , NO 2 , and SO 2 up to a lag of 21 days. We further conducted multi-pollutant models and stratified our analysis by age group, sex, and season.
Results: The overall relative risk (95% confidence interval (CI)) for PM 10 , NO 2 , and SO 2 at lag 0-1 for hospital admissions due to respiratory disease (RD) were 1.9% (0.5-3.2%), 2.3% (0.6-4%), and 1.1% (-0.2-2.4%), respectively. For cardiovascular disease (CVD), these values were 2.1% (0.6-3.5%), 1% (-0.8-2.8%), and -0.3% (-1.6-1.1%), respectively, per inter-quartile range increase of 12 µg/m 3 for PM 10 , 7.3 µg/m 3 for NO 2 , and 3.6 µg/m 3 for SO 2 . The overall cumulative risks for RD per IQR increase in PM 10 and NO 2 for children were 2% (0.2-3.9%) and 3.1% (0.7-5.6%), respectively.
Conclusion: We found robust associations of daily respiratory disease hospital admissions with daily PM 10 and NO 2 concentrations. Associations were strongest among children and warm season for RD.
Databáze: MEDLINE
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