Influence of psoriasis lesions' location and severity on psychosocial disability and psychopathology. Observational study and psychometric validation of the SAPASI Portuguese version.

Autor: Teixeira A; TOXRUN - Unidade de Investigação em Toxicologia, Instituto Universitário de Ciências da Saúde, CESPU, CRL, 4585-116 Gandra, Portugal; UCIBIO, REQUIMTE, Laboratório de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal., Ribeiro C; Instituto Universitário de Ciências da Saúde, CESPU, CRL, 4585-116 Gandra, Portugal., Gaio R; Centro de Matemática da Universidade do Porto & Departamento de Matemática, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, s/n, 4169-007 Porto, Portugal., Torres T; Serviço de Dermatologia, Centro Hospitalar do Porto, Hospital de Santo António, Rua D. Manuel II, Ex. CICAP, 4099-001 Porto, Portugal., Magina S; Serviço de Dermatologia, Centro Hospitalar de São João e Departamento de Farmacologia e Terapêutica, Faculdade de Medicina, Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal., Pereira T; Centro de Dermatologia Epidermis, Instituto CUF, R. Fonte das Sete Bicas, 170, 4460-188 Senhora da Hora, Portugal., Teixeira M; TOXRUN - Unidade de Investigação em Toxicologia, Instituto Universitário de Ciências da Saúde, CESPU, CRL, 4585-116 Gandra, Portugal. Electronic address: maribel.teixeira@iucs.cespu.pt., Rocha JC; Instituto Universitário de Ciências da Saúde, CESPU, CRL, 4585-116 Gandra, Portugal., Lobo JMS; UCIBIO, REQUIMTE, Laboratório de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal., Almeida IF; UCIBIO, REQUIMTE, Laboratório de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. Electronic address: ifalmeida@ff.up.pt., Vidal DG; UFP Energy, Environment and Health Research Unit (FP-ENAS), University Fernando Pessoa (UFP), Praça 9 de Abril 349, 4249-004 Porto, Portugal., Pedrosa E Sousa HF; Department of Mathematics (DM.UTAD), University of Trás-os-Montes and Alto Douro (UTAD), Quinta de Prados, 5001-801 Vila Real, Portugal., Dinis MAP; UFP Energy, Environment and Health Research Unit (FP-ENAS), University Fernando Pessoa (UFP), Praça 9 de Abril 349, 4249-004 Porto, Portugal., Almeida V; UCIBIO, REQUIMTE, Laboratório de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal; UNIPRO - Unidade de Investigação em Patologia e Reabilitação Oral, Instituto Universitário de Ciências da Saúde (IUCS), CESPU, 4585-116 Gandra, Portugal.
Jazyk: angličtina
Zdroj: Journal of psychosomatic research [J Psychosom Res] 2022 Mar; Vol. 154, pp. 110714. Date of Electronic Publication: 2022 Jan 06.
DOI: 10.1016/j.jpsychores.2021.110714
Abstrakt: Objectives: The psychosocial impact of psoriasis is well documented. However, the contributing role of clinical disease characteristics is not satisfactorily explored. This study aimed to validate the Self-administered Psoriasis Area and Severity Index (SAPASI) to a Portuguese population (SAPASI-PT) and to perform its cross-validation, assessing how the results will generalize to an independent data set, with the Psoriasis Area and Severity Index (PASI), in order to assess the influence of psoriasis' severity on psychosocial disability and psychopathology.
Methods: A cross-sectional study with 228 patients with psoriasis was carried out. Data was collected through a sociodemographic and clinical questionnaire, SAPASI-PT, the Psoriasis Disability Index (PDI) and the Brief Symptoms Inventory (BSI). The cultural and linguistic adaptation of SAPASI to a Portuguese version and the cross validation with PASI was carried out. Multiple associations between psychosocial disability, psychopathology and severity, discomfort and location of lesions were investigated through logistic regression models.
Results: A good adjustment model for SAPASI-PT is found. Also, associations between psychosocial disability, psychopathology and the psoriasis severity and discomfort are found. The existence of lesions is positively associated with the severity of the disease. Patients with lesions in hands or genitals are those reporting a greater discomfort. The presence of lesions in hands is positively associated with PDI, i.e., with leisure and with treatment, marginally. Additionally, patients scoring higher in the personal dimension are found to have a significantly greater percentage of lesions in the genitals.
Conclusions: The psoriasis severity and location of lesions are important determinants of patients´ quality of life. Lesions on face, hands and genitals are associated with a higher impact on psychosocial wellbeing of patients. Psychological counselling should be considered within psoriasis treatment context in patients with the described disease manifestations.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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