Maternal hair cortisol concentrations across pregnancy and the early postpartum period in a Puerto Rican sample.

Autor: Horan H; Department of Anthropology, Oregon State University, Corvallis, Oregon, USA.; Department of Anthropology, The University of Alabama, Tuscaloosa, Alabama, USA., Cheyney M; Department of Anthropology, Oregon State University, Corvallis, Oregon, USA., Torres EG; Advanced Obstetrics, PSC, Centro Medico Menonita, Cayey, Puerto Rico., Eick G; Department of Anthropology, Global Health Biomarker Laboratory, University of Oregon, Corvallis, Oregon, USA., Bovbjerg M; Epidemiology Program, Oregon State University, Corvallis, Oregon, USA., Snodgrass JJ; Department of Anthropology, Global Health Biomarker Laboratory, University of Oregon, Corvallis, Oregon, USA.
Jazyk: angličtina
Zdroj: American journal of human biology : the official journal of the Human Biology Council [Am J Hum Biol] 2022 Nov; Vol. 34 (11), pp. e23718. Date of Electronic Publication: 2022 Jan 10.
DOI: 10.1002/ajhb.23718
Abstrakt: Objective: Hair cortisol is a noninvasive, long-term biomarker of human stress. Strengths and weaknesses of this biomarker as a proxy measure of perinatal stress are not yet well understood. Hair cortisol data were collected from pregnant women in Puerto Rico to investigate maternal cortisol level variance across pregnancy.
Methods: In 2017, we recruited 86 pregnant women planning to birth at a large urban hospital. We aimed to collect four hair samples from each participant, one in each trimester and one in the postpartum period.
Results: Median cortisol in the first trimester (n = 82) was 5.7 picograms/milligram (pg/mg) (range: 1.0-62.4). In the second, third, and postpartum periods, the medians were 6.8 pg/mg (1.0-69.5), (n = 46), 20.1 pg/mg (5.6-89.0), (n = 30), and 14.1 pg/mg (1.7-39.8), (n = 9), respectively. These medians disguise a 10-fold and 50-fold variability for two participants. Our sample sizes declined sharply when Hurricane Maria caused major disruptions in services and participants' lives.
Conclusion: Maternal hair cortisol concentrations were lower in the first and second trimester than the third trimester and early postpartum period. We also observed a wide range of variation in cortisol levels throughout pregnancy and in the postpartum period.
(© 2022 Wiley Periodicals LLC.)
Databáze: MEDLINE
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