These organoids have some nerve: Uniting three germ layers in a human gastric model system.
| Autor: | Koppes AN; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA; Department of Bioengineering, Northeastern University, Boston, MA 02115, USA; Department of Biology, Northeastern University, Boston, MA 02115, USA. Electronic address: a.koppes@northeastern.edu., Koppes RA; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA., Nichols KN; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cell stem cell [Cell Stem Cell] 2022 Jan 06; Vol. 29 (1), pp. 5-6. |
| DOI: | 10.1016/j.stem.2021.12.005 |
| Abstrakt: | Gastrointestinal organoids provide an accessible model for studying human development and disease. In this issue of Cell Stem Cell, Eicher et al. (2022) direct human pluripotent stem cells to incorporate three germ layers into gastric organoids, recapitulating the structure and function of human gut tissue in an in vitro model. (Copyright © 2021. Published by Elsevier Inc.) |
| Databáze: | MEDLINE |
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