Upfront Adjuvant Immunotherapy of Replication Repair-Deficient Pediatric Glioblastoma With Chemoradiation-Sparing Approach.

Autor: Larkin T; Department of Pediatrics, UF Health Shands Hospital, Gainesville, FL.; Department of Oncology, St Jude Children's Research Hospital, Memphis, TN., Das A; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada.; Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Bianchi V; Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Sudhaman S; Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Chung J; Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Alsafwani N; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Negm L; Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Yachnis A; Department of Pathology, University of Florida, Gainesville, FL., Blatt J; Department of Neurosurgery and the Preston A. Wells Jr Center for Brain Tumor Therapy, University of Florida, Gainesville, FL., Hawkins C; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Bouffet E; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada., Tabori U; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada.; Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Gururangan S; Department of Neurosurgery and the Preston A. Wells Jr Center for Brain Tumor Therapy, University of Florida, Gainesville, FL.
Jazyk: angličtina
Zdroj: JCO precision oncology [JCO Precis Oncol] 2021 Nov; Vol. 5, pp. 1426-1431.
DOI: 10.1200/PO.21.00153
Abstrakt: Competing Interests: Sumedha SudhamanEmployment: Strand Life Sciences Cynthia HawkinsConsulting or Advisory Role: BayerPatents, Royalties, Other Intellectual Property: IP for low-grade glioma and sarcoma fusion panels and medulloblastoma subgrouping panel Eric BouffetConsulting or Advisory Role: NovartisResearch Funding: Roche, Bristol Myers SquibbNo other potential conflicts of interest were reported.
Databáze: MEDLINE