Quantifying Tumor and Vasculature Deformations during Laryngoscopy.

Autor: Wu X; Gordon Center for Medical Imaging at Massachusetts General Hospital and Harvard Medical School, 13th St, CNY149-5212, Charlestown, MA, 02129, USA. Xwu23@mgh.harvard.edu., Pastel DA; Department of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.; Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA., Khan R; Department of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.; Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA., Eskey CJ; Department of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.; Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA., Shi Y; Thayer School of Engineering at Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA., Sramek M; Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA., Paydarfar JA; Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.; Thayer School of Engineering at Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.; Section of Otolaryngology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA., Halter RJ; Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.; Thayer School of Engineering at Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.
Jazyk: angličtina
Zdroj: Annals of biomedical engineering [Ann Biomed Eng] 2022 Jan; Vol. 50 (1), pp. 94-107. Date of Electronic Publication: 2022 Jan 07.
DOI: 10.1007/s10439-021-02896-8
Abstrakt: Retractors and scopes used in head and neck surgery to provide adequate surgical exposure also deform critical structures in the region. Surgeons typically use preoperative imaging to plan and guide their tumor resections, however the large tissue deformation resulting from placement of retractors and scopes reduces the utility of preoperative imaging as a reliable roadmap. We quantify the extent of tumor and vasculature deformation in patients with tumors of the larynx and pharynx undergoing diagnostic laryngoscopy. A mean tumor displacement of 1.02 cm was observed between the patients' pre- and intra-operative states. Mean vasculature displacement at key bifurcation points was 0.99 cm. Registration to the hyoid bone can reduce tumor displacement to 0.67 cm and improve carotid stem angle deviations but increase overall vasculature displacement. The large deformation results suggest limitations in reliance on preoperative imaging and that using specific landmarks intraoperatively or having more intraoperative information could help to compensate for these deviations and ultimately improve surgical success.
(© 2021. Biomedical Engineering Society.)
Databáze: MEDLINE
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