Primitive myxoid mesenchymal tumor of infancy: Case report and review of the literature.

Autor:	Essaoudi MA; Pathology Laboratory, Rabat Children's Hospital, CHU Ibn Sina, Faculty of Medicine, Mohammed V University, Rabat, Morocco. Electronic address: essaoudimedamine@gmail.com., Khmou M; Pathology Laboratory, Rabat Children's Hospital, CHU Ibn Sina, Faculty of Medicine, Mohammed V University, Rabat, Morocco., Elkababri M; Department of Pediatric Oncology, Rabat Children's Hospital, CHU Ibn Sina, Faculty of Medicine, Mohammed V University, Rabat, Morocco., Rouas L; Pathology Laboratory, Rabat Children's Hospital, CHU Ibn Sina, Faculty of Medicine, Mohammed V University, Rabat, Morocco., Hessissen L; Department of Pediatric Oncology, Rabat Children's Hospital, CHU Ibn Sina, Faculty of Medicine, Mohammed V University, Rabat, Morocco., Lamalmi N; Pathology Laboratory, Rabat Children's Hospital, CHU Ibn Sina, Faculty of Medicine, Mohammed V University, Rabat, Morocco.
Jazyk:	angličtina
Zdroj:	Annales de pathologie [Ann Pathol] 2022 Nov; Vol. 42 (6), pp. 458-461. Date of Electronic Publication: 2022 Jan 03.
DOI:	10.1016/j.annpat.2021.12.005
Abstrakt:	Primitive myxoid mesenchymal tumor of infancy (PMMTI) is an extremely rare soft tissue tumor with only a few cases. Herein, we report a case of 5-months-old girl presenting with a soft tissue mass on the sole of the left foot that recurred 2months after a first resection. The Doppler ultrasound imaging showed abundant blood flow in the tumor. Magnetic resonance imaging (MRI) showed a well demarcated tumor on the sole of the left foot. The surgically resected tumor consisted of primitive mesenchymal tumor cells dispersed in a myxoid background with delicate small blood vessels. Immunohistochemically, tumor cells expressed vimentin but were negative for AE1/AE3, Desmin, Muscle-Specific Actin, MyoD1, Myogenin, CD34, S-100 protein and CD99. Fluorescence in situ hybridization (FISH) showed absence of chromosomal translocation involving SYT and ETV6. Thus, the patient was diagnosed with a primitive myxoid mesenchymal tumor of infancy. To our knowledge, this is the first case of PMMTI affecting the sole of the foot. (Copyright © 2021 Elsevier Masson SAS. All rights reserved.)
Databáze:	MEDLINE
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