| Autor: |
Hole NJ, Catty JP, Catty D |
| Jazyk: |
angličtina |
| Zdroj: |
Molecular immunology [Mol Immunol] 1987 Jan; Vol. 24 (1), pp. 75-82. |
| DOI: |
10.1016/0161-5890(87)90113-1 |
| Abstrakt: |
Rabbit anti-rabbit idiotype antibody was raised to both clonally heterogeneous and restricted auto anti-b6 antibodies induced in b6 allotype-suppressed (b6)/(b6) homozygous and b4/(b6) heterozygous rabbits. In every case the anti-idiotypic antibodies were specific only for the inducing antibody as shown by direct binding solid-phase RIA. Anti-idiotypes directed to the same antibody preparation had a similar but not identical specificity. It was demonstrated by IEF that the same idiotype specificity (spectrotype) was present throughout the anti-b6 response in individual rabbits. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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