Characteristics of patients diagnosed with cervical cancer in Brazil: preliminary results of the prospective cohort EVITA study (EVA001/LACOG 0215).

Autor:	Rodrigues AN; Universidade Federal de Minas Gerais, Belo Horizonte, Brazil angelica.onco@me.com.; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil.; EVA - Brazilian Gynecologic Oncology Group, Belo Horizonte, Brazil., de Melo AC; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil.; EVA - Brazilian Gynecologic Oncology Group, Belo Horizonte, Brazil.; Brazilian National Cancer Institute - INCA, Rio de Janeiro, Brazil., Calabrich AFC; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil.; EVA - Brazilian Gynecologic Oncology Group, Belo Horizonte, Brazil.; Clínica Assistência Multidisciplinar em Oncologia, Salvador, Brazil., Cronenberger E; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil.; Clinical Research, Centro Regional Integrado de Oncologia, Fortaleza, Ceara, Brazil., Torres KL; Fundação Centro de Controle de Oncologia do Estado do Amazonas, Manaus, Brazil., Damian F; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil.; Centro de Pesquisa em Oncologia, Porto Alegre, Brazil., Cossetti R; Hospital do Cancer Aldenora Bello, Sao Luis, Brazil., de Azevedo CRAS; Medical Oncology, Instituto de Medicina Integral Professor Fernando Figueira, Recife, Brazil., da Fonseca AJ; Hospital Geral de Roraima, Boa Vista, Brazil., Nerón Y; Centro de Pesquisas Oncologicas, Florianopolis, Santa Catarina, Brazil., Nunes J; Hospital Erasto Gaertner, Curitiba, Paraná, Brazil., Lopes A; Instituto Brasileiro de Controle do Cancer, Sao Paulo, São Paulo, Brazil., Thomé F; Hospital Sao Vicente de Paulo, Passo Fundo, RS, Brazil., Leal R; Universidade Federal do Ceara Hospital Universitario Walter Cantidio, Fortaleza, CE, Brazil., Borges G; Clínica Neoplasias Litoral, Itajaí, Brazil., da Silva AF; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil., Rodrigues MF; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil., Nunes Filho PRS; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil., Zaffaroni F; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil., Freitas RDS; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil., Werutsky G; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil., Maluf F; Latin American Cooperative Oncology Group, Porto Alegre, Rio Grande do Sul, Brazil.; EVA - Brazilian Gynecologic Oncology Group, Belo Horizonte, Brazil.; Hospital Beneficência Portuguesa de São Paulo, São Paulo, Brazil.
Jazyk:	angličtina
Zdroj:	International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2022 Feb; Vol. 32 (2), pp. 141-146. Date of Electronic Publication: 2021 Dec 29.
DOI:	10.1136/ijgc-2021-002972
Abstrakt:	Objectives: Cervical cancer is the fourth most common cancer in women worldwide. Epidemiological and quality of life (QoL) data in patients with cervical cancer from low- and middle-income countries are scarce. We aimed to describe sociodemographic and clinicopathological characteristics and quality of life of patients with cervical cancer at diagnosis in Brazil. Methods: EVITA is a prospective cohort study of newly diagnosed patients with cervical cancer from May 2016 to December 2017, stages I-IVB, from 16 Brazilian sites representing the five Brazilian regions. At baseline, medical evaluation was performed and European Organization for Research and Treatment of Cancer (EORTC) QLQ-CX24/C30 questionnaires were administered. Results: A total of 631 patients were included. Mean±SD age was 49.3±13.9 years; skin color was non-white in 65.3%, and 68.0% had ≤8 years of formal education. In total, 85.1% of patients had a Pap smear. The main reasons reported by patients for not having a Pap smear were: lack of interest (46.9%), shame or embarrassment (19.7%), lack of knowledge (19.7%), and difficulty with access (9.1%). Most patients were diagnosed with locally advanced or metastatic disease (FIGO clinical stage II-IV in 81.8%- stage II in 35.2%, stage III in 36.1%, and stage IV in 10.5%). Patients with clinical stage III-IV had worse physical functioning and role functioning. Conclusions: Cervical cancer in Brazil is usually diagnosed at an advanced stage. Most patients have low formal education and are unemployed. Lack of interest was identified as a main reason for not having a screening test, and limited access was reported as a reason by <10% of the patients. Awareness campaigns must be a governmental priority, specially focused on the needy population, along with wide access to treatment. Competing Interests: Competing interests: None declared. (© IGCS and ESGO 2022. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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