Bilateral Sensorineural Hearing Loss in the Setting of Acute Methamphetamine Overdose.

Autor: Reich JS; Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA., Sethi HK; Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA.; Department of Otolaryngology-Head and Neck Surgery, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA., Sataloff RT; Department of Otolaryngology-Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania, PA, USA.
Jazyk: angličtina
Zdroj: Ear, nose, & throat journal [Ear Nose Throat J] 2024 Aug; Vol. 103 (8), pp. NP491-NP493. Date of Electronic Publication: 2021 Dec 29.
DOI: 10.1177/01455613211069353
Abstrakt: Substance abuse is a rare but known cause of sensorineural hearing loss (SNHL). We report a case of acute SNHL in a 28-year-old man following an overdose of methamphetamine and incidental ingestion of fentanyl. On initial encounter, he had moderate-to-severe hearing loss in the right ear and severe-to-profound hearing loss in the left ear in addition to acute kidney injury, liver failure, and lactic acidosis. The patient was treated with a two-week course of high-dose steroids and expressed a subjective improvement in hearing. This case highlights the importance of auditory testing following a drug overdose and is one of the only documented cases of hearing loss following methamphetamine use in recent years. There is a paucity of literature regarding the mechanism causing acute SNHL secondary to methamphetamines. Proposed etiologies include neurotransmitter depletion or reduced cochlear blood flow as possible causes of ototoxicity.
Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE