Suspend or amend? Randomized controlled trial on neuropsychological rehabilitation for epilepsy: A COVID-19 impact.

Autor:	Sharma S; Neuropsychology, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India., Nehra A; Neuropsychology, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India., Pandey S; Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India., Tripathi M; Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India., Srivastava A; Department of Neurology, All India Institute of Medical Sciences, New Delhi, India., Padma MV; Department of Neurology, All India Institute of Medical Sciences, New Delhi, India., Garg A; Department of Neuroradiology, All India Institute of Medical Sciences, New Delhi, India., Pandey RM; Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India., Chandra S; Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India., Tripathi M; Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Jazyk:	angličtina
Zdroj:	Epilepsy & behavior reports [Epilepsy Behav Rep] 2022; Vol. 17, pp. 100516. Date of Electronic Publication: 2021 Dec 16.
DOI:	10.1016/j.ebr.2021.100516
Abstrakt:	COVID-19 caused devastating effects of human loss and suffering along with disruption in clinical research, forcing reconceptualization and modification of studies. This paper attempts to outline the steps followed and detail the modifications undertaken to deal with the impacts of the pandemic on the first ongoing randomized controlled trial on effectiveness of neuropsychological rehabilitation in adult patients with drug-resistant epilepsy in India. All modifications were based on evolving guidelines and circumstantial context and were planned, reviewed and approved by important stakeholders. Results obtained from the trial need to be interpreted and analysed within this context. These modifications have implications for wider outreach of neuropsychology services in India. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2021 The Authors.)
Databáze:	MEDLINE
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