Human mesenchymal stem cells.

Autor: Chen X; Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-Sen University, Guangzhou, China., Huang J; Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-Sen University, Guangzhou, China., Wu J; Chinese Society for Stem Cell Research, Shanghai, China.; National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China., Hao J; Chinese Society for Stem Cell Research, Shanghai, China.; National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China., Fu B; Chinese Society for Stem Cell Research, Shanghai, China.; China National Institute of Metrology, Beijing, China., Wang Y; Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China., Zhou B; Chinese Society for Stem Cell Research, Shanghai, China.; Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China., Na T; National Institutes for Food and Drug Control, Beijing, China., Wei J; Chinese Society for Stem Cell Research, Shanghai, China.; Zephyrm Biotechnologies Co., Ltd, Beijing, China., Zhang Y; Chinese Society for Stem Cell Research, Shanghai, China.; HHLIFE Company Inc. Shenzhen, Shenzhen, China., Li Q; Chinese Society for Stem Cell Research, Shanghai, China.; China National GeneBank, Shenzhen, China., Hu S; Chinese Society for Stem Cell Research, Shanghai, China.; Department of Cardiovascular Surgery of the First Affiliated Hospital & Institute for Cardiovascular Science, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Medical College, Soochow University, Suzhou, China., Zhou J; Chinese Society for Stem Cell Research, Shanghai, China.; Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China., Yu J; Chinese Society for Stem Cell Research, Shanghai, China.; Nuwacell Biotechnology Co., Ltd, Hefei City, China., Wu Z; China Medicinal Biotech Association, Beijing, China., Zhu H; Chinese Society for Stem Cell Research, Shanghai, China.; National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China., Cao J; Chinese Society for Stem Cell Research, Shanghai, China.; National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China., Wang L; Chinese Society for Stem Cell Research, Shanghai, China.; National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China., Peng Y; Chinese Society for Stem Cell Research, Shanghai, China.; National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China., Liang L; Chinese Society for Stem Cell Research, Shanghai, China.; National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China., Ma A; Chinese Society for Stem Cell Research, Shanghai, China.; Beijing Technology and Business University, Beijing, China., Zhang Y; Chinese Society for Stem Cell Research, Shanghai, China.; Zephyrm Biotechnologies Co., Ltd, Beijing, China., Zhao T; Chinese Society for Stem Cell Research, Shanghai, China.; National Stem Cell Resource Center, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China., Xiang AP; Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-Sen University, Guangzhou, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Jazyk: angličtina
Zdroj: Cell proliferation [Cell Prolif] 2022 Apr; Vol. 55 (4), pp. e13141. Date of Electronic Publication: 2021 Dec 22.
DOI: 10.1111/cpr.13141
Abstrakt: Mesenchymal stem cells (MSCs) have attracted great interest for cell therapy and tissue regeneration due to their self-renewal capacity, multipotency and potent immunomodulatory effects on immune cells. However, heterogeneity of MSCs has become a prominent obstacle to limit their translation into practice, as cells from different tissue sources or each individual have great differences in their transcriptomic signatures, differentiation potential and biological functions. Therefore, there is an urgent need for consensus standard for the quality control and technical specifications of MSCs. 'Human Mesenchymal Stem Cells' is the latest set of guidelines on hMSC in China, jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packaging requirements, storage requirements, transportation requirements and waste disposal requirements for hMSC, which is applicable to the quality control for hMSC. It was originally released by the China Society for Cell Biology on 9 January 2021. We hope that publication of these guidelines will facilitate institutional establishment, acceptance and execution of proper protocols, and accelerate the international standardization of hMSC for clinical development and therapeutic applications.
(© 2021 The Authors. Cell Proliferation published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje