A Comparative Study of Children with MIS-C between Admitted to the Pediatric Intensive Care Unit and Pediatric Ward: A One-Year Retrospective Study.

Autor:	Kıymet E; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Böncüoğlu E; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Şahinkaya Ş; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Cem E; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Çelebi MY; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Düzgöl M; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Kara AA; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Arıkan KÖ; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Vuran GT; Department of Pediatric Cardiology, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Yılmazer MM; Department of Pediatric Cardiology, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Sandal ÖS; Department of Pediatric Intensive Care, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Ağın H; Department of Pediatric Intensive Care, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Pirinç N; Department of Pediatrics, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Bayram N; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey., Devrim İ; Department of Paediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir 35210, Turkey.
Jazyk:	angličtina
Zdroj:	Journal of tropical pediatrics [J Trop Pediatr] 2021 Dec 08; Vol. 67 (6).
DOI:	10.1093/tropej/fmab104
Abstrakt:	Objectives: This descriptive study aimed to compare the clinical and laboratory features of the children with the multisystem inflammatory syndrome in children (MIS-C), requiring pediatric intensive care unit (PICU), admission with the MIS-C patients who did not require PICU admission. Patients and Methods: This study was conducted between March 2020 and February 2021 at the University of Health Sciences Dr. Behçet Uz Children's Hospital, a referral center for pediatric infectious diseases in the Aegean Region of Turkey. All hospitalized patients aged 18 years old or less with MIS-C according to the definition of the universal guidelines were included in the study. Data of the patients with the diagnosis of MIS-C were recorded and collected from the electronic medical records of the hospital. The data included demographic characteristics, presenting signs and symptoms, laboratory findings and clinical data. Results: A total of 58 patients with MIS-C were included in this study. Thirty-eight (65.5%) patients were male. The median age was 6 years (2 months-16 years). The patients admitted to PICU were 15 (25.9%). The rate of pulmonary involvement was 81.3% (n = 13) in the PICU group. The median procalcitonin, C-reactive protein, erythrocyte sedimentation rate, D-Dimer and ferritin values were significantly higher in the PICU group compared to non-PICU group (p < 0.001, p = 0.02, p < 0.001, p = 0.006 and p = 0.031). Conclusions: Besides the depressing cardiac functions reported before, the pulmonary involvement and signs of shock are important factors for PICU admission in children with MIS-C. (© The Author(s) [2021]. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
Databáze:	MEDLINE
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