Establishing Clinical Cut-points on the Pediatric PROMIS-Pain Interference Scale in Youth With Abdominal Pain.

Autor:	Gamwell KL; Department of Pediatrics, University of South Carolina School of Medicine Greenville.; Department of Pediatric Pain Medicine, Prisma Health Children's Hospital, Greenville, SC., Mara CA; Department of Pediatrics,College of Medicine, University of Cincinnati.; Division of Behavioral Medicine and Clinical Psychology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Hommel KA; Department of Pediatrics,College of Medicine, University of Cincinnati.; Division of Behavioral Medicine and Clinical Psychology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Kashikar-Zuck S; Department of Pediatrics,College of Medicine, University of Cincinnati.; Division of Behavioral Medicine and Clinical Psychology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Cunningham NR; Department of Family Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI.
Jazyk:	angličtina
Zdroj:	The Clinical journal of pain [Clin J Pain] 2021 Dec 17; Vol. 38 (3), pp. 173-181. Date of Electronic Publication: 2021 Dec 17.
DOI:	10.1097/AJP.0000000000001012
Abstrakt:	Objective: Abdominal pain is a common presenting complaint in youth seeking medical care and can be debilitating. Therefore, it is important to understand the impact of pain on functioning using a clinically sensitive approach. The National Institutes of Health has established a common core of psychometrically precise measures through the Patient-Reported Outcomes Measurement Information System (PROMIS) initiative. The Pediatric PROMIS-Pain Interference (PPPI) scale was developed to measure pain-related interference, drawing from existing legacy measures. However, its clinical validity has not been thoroughly established in clinical populations. The current study sought to develop clinical cut-points and investigate the validity of the PPPI in a large sample (N=5281) of youth presenting to gastroenterological care with abdominal pain symptoms. Materials and Methods: Convergent validity of the PPPI was investigated. Quartile and tertile groupings of the PPPI were calculated and compared with cut-points derived from healthy populations and mixed convenience samples on clinical outcomes via multivariate analyses of variance. Results: There was good evidence of convergent validity. The tertile solution was superior in classifying different levels of pain-related outcomes as compared with other cut-points. The tertile solution suggested the following PPPI groupings: minimal (≤51), moderate (52 to 59), and severe (≥60). Discussion: Results suggest the PPPI is a valid measure with clinically meaningful cut-points to assess pain-related interference in youth with abdominal pain. Competing Interests: This work was supported by the Sharon S. Keller American Pain Society Grant, a Cincinnati Children’s Hospital Place Outcomes Award, Cincinnati, Ohio and an early career award from the National Institutes of Health NCCIH (grant no. K23AT009458), all of which were awarded to the senior author (N.R.C.). The first author’s (K.L.G.) efforts were supported by a training grant (grant no. T32HD068223) from the National Institutes of Health NICHD. Co-author S.K.-Z.’s effort was partially supported by a mid-career award in patient-oriented research (grant no. K24AR056687) from the National Institutes of Health NIAMS. The authors declare no conflict of interest. (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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