Fraction of COVID-19 hospitalizations and deaths attributable to chronic diseases.

Autor: Reyes-Sánchez F; National Institute of Public Health, Population Health Research Center, Mexico., Basto-Abreu A; National Institute of Public Health, Population Health Research Center, Mexico. Electronic address: ana.basto@insp.mx., Torres-Alvarez R; National Institute of Public Health, Population Health Research Center, Mexico., Canto-Osorio F; National Institute of Public Health, Population Health Research Center, Mexico., González-Morales R; National Institute of Public Health, Population Health Research Center, Mexico., Dyer-Leal DD; Ministry of Health, General Direction of Health Information, Mexico., López-Ridaura R; Ministry of Health, National Center for Preventive Programs and Disease Control, Mexico., Zaragoza-Jiménez CA; Ministry of Health, Director of Epidemiological Information, Mexico., Rivera JA; National Institute of Public Health, Mexico., Barrientos-Gutiérrez T; National Institute of Public Health, Population Health Research Center, Mexico.
Jazyk: angličtina
Zdroj: Preventive medicine [Prev Med] 2022 Feb; Vol. 155, pp. 106917. Date of Electronic Publication: 2021 Dec 16.
DOI: 10.1016/j.ypmed.2021.106917
Abstrakt: Evidence shows that chronic diseases are associated with COVID-19 severity and death. This study aims to estimate the fraction of hospitalizations and deaths from COVID-19 attributable to chronic diseases associated to poor nutrition and smoking among adults who tested positive to COVID-19 in Mexico. We analyzed 1,006,541 adults aged ≥20 who tested positive for COVID-19 from March 23 to December 5, 2020. Six chronic diseases were considered: obesity, chronic obstructive pulmonary disease (COPD), hypertension, diabetes, cardiovascular disease, and chronic kidney disease (CKD). We calibrated the database using a bias quantification method to consider undiagnosed disease cases. To estimate the total impact of multiple diseases, we defined a multimorbidity variable according to the number of diseases. Risks of hospitalization and death were estimated with Poisson regression models and used to calculate population attributable fractions (PAFs). Chronic diseases accounted for to 25.4% [95% CI: 24.8%-26.1%], 28.3% (95% CI: 27.8%-28.7%) and 15.3% (95% CI: 14.9%-15.7%) of the hospitalizations among adults below 40, 40-59, and 60 years and older, respectively. For COVID-19-related deaths, 50.1% (95% CI: 48.6%-51.5%), 40.5% (95% CI: 39.7%-41.3%), and 18.7% (95% CI, 18.0%-19.5%) were attributable to chronic diseases in adults under 40, 40-59, and 60 years and older, respectively. Chronic diseases linked to poor nutrition and smoking could have contributed to a large burden of hospitalization and deaths from COVID-19 in Mexico, particularly among younger adults. Medical and structural interventions to curb chronic disease incidence and facilitate disease control are urgently needed.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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