[Ocular manifestations associated to CD4+ in patients with human immunodeficiency virus].

Autor: Ponce-Horta AM; Instituto Mexicano del Seguro Social, Centro Médico Nacional de Occidente, Hospital de Especialidades 'Lic. Ignacio García Téllez', Servicio de Oftalmología. Guadalajara, Jalisco, México., Ponce-Horta EAF; Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Área de Orientación Educativa. Guadalajara, Jalisco, México., Valencia-Paredes D; Instituto Mexicano del Seguro Social, Centro Médico Nacional de Occidente, Hospital de Especialidades 'Lic. Ignacio García Téllez', Servicio de Oftalmología. Guadalajara, Jalisco, México., García-Contreras MS; Instituto Mexicano del Seguro Social, Centro Médico Nacional de Occidente, Hospital de Especialidades 'Lic. Ignacio García Téllez', Servicio de Oftalmología. Guadalajara, Jalisco, México., Arias-González NP; Instituto Mexicano del Seguro Social, Centro Médico Nacional de Occidente, Hospital de Especialidades 'Lic. Ignacio García Téllez', Servicio de Oftalmología. Guadalajara, Jalisco, México.
Jazyk: Spanish; Castilian
Zdroj: Revista medica del Instituto Mexicano del Seguro Social [Rev Med Inst Mex Seguro Soc] 2021 Sep 01; Vol. 59 (5), pp. 417-422. Date of Electronic Publication: 2021 Sep 01.
Abstrakt: Background: Since the first cases of human immunodeficiency virus (HIV), ocular manifestations secondary to infection have been known and these have been related to the CD4+ lymphocyte count.
Objective: To describe the correlation between ocular manifestations in patients with HIV and the CD4+ lymphocyte count.
Material and Methods: Analytical cross-sectional study of patients with HIV whose CD4+ count was correlated with the presence of ophthalmological manifestations.
Results: 21 patients between 26 and 67 years were studied. Only 3 patients were not on antiretroviral therapy. 67% of the patients presented some type of ocular manifestation, 42% presented non-infection related manifestations, 47% related manifestations and 24% both. Conjunctival microangiopathy was the most frequent ocular manifestation (35.7%). There was a statistically significant correlation (r = 0.76, p = 0.0001) between eye manifestations related to infection and CD4+ lymphocyte count.
Conclusions: Patients with HIV frequently present ocular manifestations, the majority related to infection; there is a correlation between the presence of these with the CD4+ count. However, a similar number of manifestations not related to infection occurred without correlation with the count; therefore, HIV patients should have periodic ophthalmological examinations, independently of CD4+ count.
(© 2021 Instituto Mexicano del Seguro Social.)
Databáze: MEDLINE
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