Effect of adding magnifying BLI, magnifying NBI, and iodine staining to white light imaging in diagnosis of early esophageal cancer.

Autor: Kawada K; Tokyo Medical and Dental University, Department of Gastrointestinal Surgery, Tokyo, Japan, Saitama Cancer center, Department of Gastroenterology., Arima M; Saitama Cancer center, Department of Gastroenterology, Ina-machi, Kitaadachi, Japan., Miyahara R; Nagoya University Graduate School of Medicine, Department of Gastroenterology and Hepatology, Nagoya, Japan., Tsunomiya M; Saitama Cancer center, Department of Gastroenterology, Ina-machi, Kitaadachi, Japan., Kikuchi M; Nagoya University Graduate School of Medicine, Department of Gastroenterology and Hepatology, Nagoya, Japan., Yamamoto F; Nagoya University Graduate School of Medicine, Department of Gastroenterology and Hepatology, Nagoya, Japan., Hoshino A; Tokyo Medical and Dental University, Department of Gastrointestinal Surgery, Tokyo, Japan, Saitama Cancer center, Department of Gastroenterology., Nakajima Y; Tokyo Medical and Dental University, Department of Gastrointestinal Surgery, Tokyo, Japan, Saitama Cancer center, Department of Gastroenterology., Kinugasa Y; Tokyo Medical and Dental University, Department of Gastrointestinal Surgery, Tokyo, Japan, Saitama Cancer center, Department of Gastroenterology., Kawano T; Soka Municipal hospital, Department of Surgery, Soka city, Saitama, Japan.
Jazyk: angličtina
Zdroj: Endoscopy international open [Endosc Int Open] 2021 Dec 14; Vol. 9 (12), pp. E1877-E1885. Date of Electronic Publication: 2021 Dec 14 (Print Publication: 2021).
DOI: 10.1055/a-1583-9196
Abstrakt: Background and study aims  We investigated the effect of adding magnifying blue laser imaging (BLI), magnifying narrow-band imaging (NBI), and iodine staining to white light imaging in diagnosis of early esophageal squamous cell carcinoma (EESCC) in high-risk patients. Patients and methods  Between May 2013 and March 2016, two parallel prospective cohorts of patients received either primary WLI followed by NBI-magnifying endoscopy (ME) or primary WLI followed by BLI-ME, were studied. At the end of screening, both groups underwent iodine staining. The percentage of patients with newly detected esophageal malignant lesions in each group and the diagnostic ability of image-enhanced endoscopy (IEE)-ME were evaluated. Results  There are 258 patients assigned to the NBI-ME group and 254 patients assigned to the BLI-ME group. The percentage of patients with one or more malignant lesions detected in the WLI + NBI-ME examination was similar in the WLI + BLI-ME examination (15 of 258 patients or 5.81 % vs. 14 of 254 patients or 5.51 %). However, four of 19 lesions in the NBI-ME group and six of 21 lesions in the BLI-ME group were overlooked and were detected by iodine staining. NBI-ME and BLI-ME showed similar accuracy in differentiation of cancerous lesions from non-cancerous lesions in diagnosis of EESCC (NBI/BLI: sensitivity, 87.5/89.5; specificity, 78.9/76.6; accuracy, 80.8/79.5; positive predictive value, 53.8/53.1; negative predictive value, 95.7/96.1). Conclusions  Both NBI and BLI were useful for detection of EESCC. However, because some lesions were overlooked by even NBI and BLI, high-risk patients may benefit from use of iodine staining during endoscopic screening of EESCC (UMIN000023596).
Competing Interests: Competing interests Dr. Kawada has received lecture fees from FUJI FILM.
(The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
Databáze: MEDLINE
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