Promoting high T 2 contrast in Dy-doped MSNs through Curie effects.

Autor: Ellis CM; Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK. jason.davis@chem.ox.ac.uk., Pellico J; Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK. jason.davis@chem.ox.ac.uk.; School of Biomedical Engineering & Imaging Sciences, King's College London, St. Thomas' Hospital, London, SE1 7EH, UK., Young LAJ; Department of Physiology, Anatomy & Genetics, University of Oxford, South Parks Road, Oxford, OX1 3PT, UK.; Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, University of Oxford, Level 0, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Miller J; Department of Physiology, Anatomy & Genetics, University of Oxford, South Parks Road, Oxford, OX1 3PT, UK.; Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, University of Oxford, Level 0, John Radcliffe Hospital, Oxford, OX3 9DU, UK.; Department of Physics, Clarendon Laboratory, Parks Road, Oxford, OX1 3PU, UK., Davis JJ; Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK. jason.davis@chem.ox.ac.uk.
Jazyk: angličtina
Zdroj: Journal of materials chemistry. B [J Mater Chem B] 2022 Jan 05; Vol. 10 (2), pp. 302-305. Date of Electronic Publication: 2022 Jan 05.
DOI: 10.1039/d1tb01894a
Abstrakt: Contrast agents retaining high relaxivities at ultrahigh magnetic fields underpin an enhanced image sensitivity within derived MRI scans. By varying the Dy 3+ loading density inside a mesoporous silica architecture the dominant Curie effect can be effectively tuned so as to optimise T 2 contrast at magnetic fields as high as 11.7 T.
Databáze: MEDLINE