Association of Anemia With Epilepsy and Antiepileptic Drugs.

Autor:	Padda J; Internal Medicine, JC Medical Center, Orlando, USA., Khalid K; Internal Medicine, JC Medical Center, Orlando, USA., Syam M; Internal Medicine, JC Medical Center, Orlando, USA., Kakani V; Internal Medicine, JC Medical Center, Orlando, USA., Kankeu Tonpouwo G; Internal Medicine, JC Medical Center, Orlando, USA., Dhakal R; Internal Medicine, JC Medical Center, Orlando, USA., Padda S; Internal Medicine, JC Medical Center, Orlando, USA., Cooper AC; Internal Medicine, JC Medical Center, Orlando, USA., Jean-Charles G; Internal Medicine, JC Medical Center, Orlando, USA.; Internal Medicine, AdventHealth and Orlando Health Hospital, Orlando, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2021 Nov 07; Vol. 13 (11), pp. e19334. Date of Electronic Publication: 2021 Nov 07 (Print Publication: 2021).
DOI:	10.7759/cureus.19334
Abstrakt:	Epilepsy is a disorder that causes unprovoked seizures regularly. It affects between 1% and 3% of the population. After the first seizure, the chances of having another one are almost 40%-52%. The etiology of febrile seizures in children with sickle cell disease is still unknown. In some groups, iron deficiency anemia has been linked to an increased risk of seizures. Although the reason and process are uncertain, some people believe that taking iron supplements can help prevent seizures. This literature covers haptene, non-haptene immune-related hemolysis, and oxidative processes activated by anti-seizure medications (ASMs). In epileptic patients, ASMs can cause anemia. Folic acid can be given to carbamazepine-treated anemic patients. There is growing evidence that it improves hemoglobin and leukocytes in individuals who take it. Therefore, one of the most efficient strategies to avoid future seizures is to take ASMs daily to maintain an even level of anticonvulsant in the body. To prevent further seizures, lifestyle changes are essential. Further studies and clinical trials are warranted to prove a clear association between epilepsy and hematologic disease, which will improve quality of life in the future. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Padda et al.)
Databáze:	MEDLINE
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