Case report and strategies to mitigate passive hemolysis with platelet transfusions in children.
| Autor: | Augustine M; Division of Transfusion Medicine, Malabar Cancer Centre, Thalassery, Kerala, India., Murugesan M; Division of Transfusion Medicine, Malabar Cancer Centre, Thalassery, Kerala, India., Gopakumar KG; Division of Pediatric Oncology, Malabar Cancer Centre, Thalassery, Kerala, India., Jithin TK; Division of Pediatric Oncology, Malabar Cancer Centre, Thalassery, Kerala, India. |
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| Jazyk: | angličtina |
| Zdroj: | Asian journal of transfusion science [Asian J Transfus Sci] 2021 Jul-Dec; Vol. 15 (2), pp. 229-232. Date of Electronic Publication: 2021 Nov 01. |
| DOI: | 10.4103/ajts.ajts_25_21 |
| Abstrakt: | Mismatched platelet concentrate transfusion due to inadequately maintained inventories is relatively common and in most instances do not cause any untoward event in adults. The cases of passive hemolysis following a mismatched apheresis platelet transfusion are common but are relatively rare with platelet concentrates. We report here a case of a nine year old boy who received three units of mismatched platelet concentrates(PC) followed by acute hemolysis. On further investigation, one of the donors of the PC, who was typed as O positive, found to have high anti-A and anti-B titres of 1:128. This highlights the importance of matched platelet transfusions or modifying the product in pediatric setting, who are susceptible for passive hemolysis. Competing Interests: There are no conflicts of interest. (Copyright: © 2021 Asian Journal of Transfusion Science.) |
| Databáze: | MEDLINE |
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