Paradoxical psoriatic arthritis in a patient with psoriasis treated with guselkumab.

Autor: Carriero A; Rheumatology Institute of Lucania (IReL), Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy.; Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy., Lubrano E; Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy., Picerno V; Rheumatology Institute of Lucania (IReL), Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy., Padula AA; Rheumatology Institute of Lucania (IReL), Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy., D'Angelo S; Rheumatology Institute of Lucania (IReL), Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy.
Jazyk: angličtina
Zdroj: Clinical and experimental dermatology [Clin Exp Dermatol] 2022 Apr; Vol. 47 (4), pp. 783-785. Date of Electronic Publication: 2022 Jan 05.
DOI: 10.1111/ced.15061
Abstrakt: Paradoxical psoriatic arthritis (PPsA) may be associated with guselkumab treatment. We describe a patient in whom PPsA required a change from guselkumab to ixekizumab. The pathophysiology of this paradoxical reaction is most likely a cytokine imbalance.
(© 2021 British Association of Dermatologists.)
Databáze: MEDLINE
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