First complete genome characterization of duck plague virus from India.

Autor: Aasdev A; Pathogenomics Lab, ICAR - National Institute of High Security Animal Diseases, Bhopal, Madhya Pradesh 462022 India., Pawar SD; Pathogenomics Lab, ICAR - National Institute of High Security Animal Diseases, Bhopal, Madhya Pradesh 462022 India.; Department of Botany, Agricultural Development Trust's Shardabai Pawar Mahila Arts, Commerce and Science College, Baramati, Maharashtra 413115 India., Mishra A; Pathogenomics Lab, ICAR - National Institute of High Security Animal Diseases, Bhopal, Madhya Pradesh 462022 India., Dubey CK; Pathogenomics Lab, ICAR - National Institute of High Security Animal Diseases, Bhopal, Madhya Pradesh 462022 India., Patil SS; ICAR-National Institute of Veterinary Epidemiology and Disease Informatics, Bengaluru, Karnataka India., Gogoi SM; Department of Microbiology, College of Veterinary Science, Assam Agricultural University, Guwahati, Assam 781022 India., Bora DP; Department of Microbiology, College of Veterinary Science, Assam Agricultural University, Guwahati, Assam 781022 India., Barman NN; Department of Microbiology, College of Veterinary Science, Assam Agricultural University, Guwahati, Assam 781022 India., Raut AA; Pathogenomics Lab, ICAR - National Institute of High Security Animal Diseases, Bhopal, Madhya Pradesh 462022 India.; Department of Translational Medicine, All India Institute of Medical Sciences Bhopal, Bhopal, Madhya Pradesh 462020 India.
Jazyk: angličtina
Zdroj: Virusdisease [Virusdisease] 2021 Dec; Vol. 32 (4), pp. 789-796. Date of Electronic Publication: 2021 Oct 29.
DOI: 10.1007/s13337-021-00748-6
Abstrakt: In this study, we report the complete genome sequencing of the Duck plague virus from India for the first time. The sequencing was done on the MinION nanopore sequencer from Oxford Nanopore Technologies. The closest relative is the European strain 2085v, with 99.98 and 99.8% identity at the amino acid and nucleotide level respectively. Moreover, 72 out of 77 ORFs are completely conserved between the 2 strains. The high similarity with the European strain over the only three other pathogenic strains reported from China points to the circulation of European strain in India. The fly pathways of migratory birds and co-habitation with native species being a probable reason. More complete genome data from diverse sampling locations are needed to characterize the genomic features, develop diagnostics, vaccines, and understand the evolution of the virus.
Competing Interests: Conflict of interestThe authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
(© The Author(s), under exclusive licence to Indian Virological Society 2021.)
Databáze: MEDLINE
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