Reasons for Hospitalization of Sickle Cell Disease Patients in the Eastern Province of Saudi Arabia: A Single-Center Study.

Autor:	Zakaria OM; Department of Surgery, College of Medicine, King Faisal University, Al-Ahsa, SAU., Buhalim RA; Department of Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Al Jabr FA; Department of Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., AlSaeed MN; Department of Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Al-Hajji IA; Department of Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Al Saleh YA; Department of Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Buhalim MA; Department of Surgery, College of Medicine, King Faisal University, Al-Ahsa, SAU., Al Dehailan AM; Department of Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2021 Nov 06; Vol. 13 (11), pp. e19299. Date of Electronic Publication: 2021 Nov 06 (Print Publication: 2021).
DOI:	10.7759/cureus.19299
Abstrakt:	Background: Sickle cell disease (SCD) is among the prevalent chronic diseases in the Eastern Province of Saudi Arabia. To our knowledge, there is no published research that reports the reasons for hospitalization in the Eastern Province of the country. Therefore, this study aimed to fill this gap. Design and Methods: This is a retrospective cohort study that was conducted in the period from January 2018 to December 2019. Patients with sickle cell disease who were admitted and treated in the hospital were included in this study. Patients' sociodemographic data and reasons for hospitalization were collected and analyzed using the statistical package for social sciences, version 21 (SPSS, Chicago, IL, USA). Results: There were 103 SCD patients, and the age range was from 18 to 62 years old. The majority of the patients were males (56.3%) and were in the younger age group (≤30 years old; 60.2%). The results showed that the most frequent cause of admission was a vaso-occlusive crisis (VOC) (n=94, 91.3%), followed by acute chest syndrome (ACS) (n=32, 31.1%), and then by hemolytic crisis (27 of the cases; 26.2%). However, we found that a higher number of hip avascular necrosis (AVN) cases were statistically significant in relation to the higher number of hospital admissions (p<0.05), whereas other reasons were not found to have a statistically significant association. Conclusion: The most frequent cause of admission was VOC episodes, followed by ACS, and then by hemolytic crises. Also, a higher number of hip AVN episodes were statistically significant with the higher number of hospital admissions. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Zakaria et al.)
Databáze:	MEDLINE
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