Efficacy of Whole-Body Vibration Training on Brain-Derived Neurotrophic Factor, Clinical and Functional Outcomes, and Quality of Life in Women with Fibromyalgia Syndrome: A Randomized Controlled Trial.

Autor:	Ribeiro VGC; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Lacerda ACR; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Santos JM; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Coelho-Oliveira AC; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Mechanical Vibration Laboratory and Integrative Practices (LAVIMPI), Biophysics and Biometrics Department, Institute of Biology Roberto Alcântara Gomes and Piquet Carneiro Polyclinic, Rio de Janeiro State University, Rio de Janeiro, Brazil., Fonseca SF; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil., Prates ACN; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Flor J; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Garcia BCC; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil., Tossige-Gomes R; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Leite HR; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Rehabilitation Sciences (PPGCR), School of Physical Education Physiotherapy and Occupational Therapy, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Fernandes JSC; Faculty of Agrarian Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Arrieiro AN; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Sartorio A; Istituto Auxologico Italiano, Division of Metabolic Diseases and Auxology & Experimental Laboratory for Auxo-endocrinological Research, Verbania, Italy., Sañudo B; Department of Physical Education and Sport, University of Seville, Seville 41013, Spain., Sá-Caputo DC; Mechanical Vibration Laboratory and Integrative Practices (LAVIMPI), Biophysics and Biometrics Department, Institute of Biology Roberto Alcântara Gomes and Piquet Carneiro Polyclinic, Rio de Janeiro State University, Rio de Janeiro, Brazil., Bernardo-Filho M; Mechanical Vibration Laboratory and Integrative Practices (LAVIMPI), Biophysics and Biometrics Department, Institute of Biology Roberto Alcântara Gomes and Piquet Carneiro Polyclinic, Rio de Janeiro State University, Rio de Janeiro, Brazil., Figueiredo PHS; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Costa HS; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Lima VP; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Cardoso RF; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Bastone AC; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Soares LA; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Mendonça VA; Integrated Center for Research and Post-Graduate Studies in Health (CIPq), Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Minas Gerais, Brazil.; Multicentric Postgraduate Program in Physiological Sciences (PPGMCF), Brazilian Society of Physiology, Diamantina, MG, Brazil.; Physiotherapy Department, Faculty of Biological Sciences and Health, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Functional Performance and Rehabilitation (PPGReab), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil., Taiar R; MATériaux et Ingénierie Mécanique (MATIM), Université de Reims Champagne-Ardenne, Reims, France.
Jazyk:	angličtina
Zdroj:	Journal of healthcare engineering [J Healthc Eng] 2021 Nov 30; Vol. 2021, pp. 7593802. Date of Electronic Publication: 2021 Nov 30 (Print Publication: 2021).
DOI:	10.1155/2021/7593802
Abstrakt:	This study aimed to investigate the efficacy of whole-body vibration training (WBVT) on blood brain-derived neurotrophic factor (BDNF) levels and determine the clinical and functional outcomes in patients with fibromyalgia syndrome (FMS). Thirty-two women with FMS were randomized into an intervention group (IG), receiving 6 weeks of WBVT, or a control group (CG) with no intervention. The outcomes at the baseline and follow-up in both groups included blood BDNF levels, sit-to-stand test (STS), 6-minute walk test (6MWT), Fibromyalgia Impact Questionnaire (FIQ), Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory (BDI), and visual analogue scale (VAS). WBVT resulted in a group-by-time interaction effect. Thus, after the intervention time, the IG had increased blood BDNF levels ( p =0.045), a higher number of repetitions on the STS test ( p =0.011), and increased walking distance on the 6MWT ( p =0.010), compared to CG. Moreover, there was a reduction in the scores of the FIQ ( p =0.001), the PSQI ( p =0.001), the BDI ( p =0.017), and pain assessed using VAS ( p =0.008) in IG. The results demonstrate that WBVT promotes an increase in blood BDNF levels, with concomitant improvement in lower limb muscle strength, aerobic capacity, clinical symptoms, and quality of life in women with FMS. This trial is registered with Brazilian Clinical Trials Registry (REBEC; RBR-38nbbx) (https://ensaiosclinicos.gov.br/rg/RBR-38nbbx). Competing Interests: The authors declare that they have no conflicts of interest. (Copyright © 2021 Vanessa G. C. Ribeiro et al.)
Databáze:	MEDLINE
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