Influence of Hypovitaminosis D on the Ocurrence of Fractures.

Autor: Valle CARD; Departamento de Ortopedia e Traumatologia, Hospital das Clínicas Samuel Libânio, Universidade do Vale do Sapucaí (Univás), Pouso Alegre, Minas Gerais, MG, Brasil., Pedri LAF; Departamento de Ortopedia e Traumatologia, Hospital das Clínicas Samuel Libânio, Universidade do Vale do Sapucaí (Univás), Pouso Alegre, Minas Gerais, MG, Brasil., Pires GB; Departamento de Ortopedia e Traumatologia, Hospital das Clínicas Samuel Libânio, Universidade do Vale do Sapucaí (Univás), Pouso Alegre, Minas Gerais, MG, Brasil., Blanco MS; Faculdade de Ciências Médicas Dr. José Garcia Coutinho, Universidade do Vale do Sapucaí (Univás), Pouso Alegre, Minas Gerais, MG, Brasil., Paula BS; Faculdade de Ciências Médicas Dr. José Garcia Coutinho, Universidade do Vale do Sapucaí (Univás), Pouso Alegre, Minas Gerais, MG, Brasil., Araújo CDM; Departamento de Ortopedia e Traumatologia, Hospital das Clínicas Samuel Libânio, Universidade do Vale do Sapucaí (Univás), Pouso Alegre, Minas Gerais, MG, Brasil.; Centro Universitário Atenas (UniAtenas), Paracatu, Minas Gerais, MG, Brasil.
Jazyk: angličtina
Zdroj: Revista brasileira de ortopedia [Rev Bras Ortop (Sao Paulo)] 2021 Nov 11; Vol. 56 (6), pp. 784-789. Date of Electronic Publication: 2021 Nov 11 (Print Publication: 2021).
DOI: 10.1055/s-0041-1729585
Abstrakt: Objective  To measure the levels of vitamin D in patients hospitalized for fractures and to evaluate its relationship with fractures. Methods  A primary, analytical, cross-sectional, non-interventional, observational, controlled study was conducted in humans. The serum measurement of: vitamin D, parathyroid hormone (PTH), calcium, phosphorus, magnesium and albumin was performed in 49 patients who were consecutively hospitalized for surgery due to fracture(s) (study group), and in 50 patients without fractures, from the various outpatient clinics, and who underwent routine tests (control group). Results  The mean level of 25-hydroxyvitamin D (25[OH]D) in patients with fractures was of 23.78 ± 8.01 ng/mL (61.22% of patients with fractures had hypovitaminosis D). The mean 25(OH)D of the control group was of 37.52 ± 9.21 ng/mL (10% of the patients had hypovitaminosis D). Most cases of hypovitaminosis (96%) did not course with secondary hyperparathyroidism (mean PTH = 41.80 ± 22.75 pg/mL). Conclusion  Hypovitaminosis D was found in a significant percentage (61.22%) of the patients who suffered fractures. Further studies on the subject are needed to better understand the influence of hypovitaminosis D on the occurrence of fractures, as well as the benefits of vitamin D supplementation in these patients.
Competing Interests: Conflito de Interesses Os autores declaram não haver conflito de interesses.
(Sociedade Brasileira de Ortopedia e Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).)
Databáze: MEDLINE
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