Safety of endoscopist-administered deep sedation with propofol in ASA III patients.

Autor: Medina-Prado L; Digestive Endoscopy, Hospital General Universitario de Alicante, España., Martínez Sempere J; Digestive Endoscopy, Hospital General Universitario de Alicante, España., Bozhychko M; Digestive Endoscopy, Hospital General Universitario de Alicante, España., Mangas-Sanjuán C; Digestive Endoscopy, Hospital General Universitario de Alicante, España., Compañy Català L; Digestive Endoscopy, Hospital General Universitario de Alicante, España., Ruiz Gómez F; Digestive Endoscopy, Hospital General Universitario de Alicante, España., Aparicio Tormo JR; Digestive Endoscopy, Hospital General Universitario de Alicante, España., Casellas Valde JA; Digestive Endoscopy, Hospital General Universitario de Alicante, España.
Jazyk: angličtina
Zdroj: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva [Rev Esp Enferm Dig] 2022 Aug; Vol. 114 (8), pp. 468-473.
DOI: 10.17235/reed.2021.8289/2021
Abstrakt: Introduction: deep sedation controlled by the endoscopist is safe in patients with low anesthetic risk (ASA I-II). However, scarce evidence is available in patients with intermediate risk (ASA III).
Objective: to evaluate the safety of deep sedation with propofol controlled by the usual endoscopy staff (endoscopist, nurse, assistant) in outpatients classified as ASA III and the risk factors for the occurrence of complications during deep sedation.
Patients and Methods: this observational and single-center cross-sectional study included consecutive patients undergoing non-complex procedures in which deep sedation was administered by the endoscopy staff. Patients were divided into group I (ASA = III) and group II (ASA < III).
Results: a total of 562 patients were included and 80 (14.2 %) were in group I. Complications related to deep sedation were more frequent in group I (23.8 % vs 14.5 %; p = 0.036), mainly mild desaturations (13.8 % vs 7.5 %; p = 0.058). Emergency intervention or death were not registered. The adjusted analysis identified age as the only independent baseline risk factor for developing global adverse events.
Conclusion: ASA III patients developed more sedation-related complications than ASA I-II patients. However, these complications were mild and did not prevent the correct performance of the procedure.
Databáze: MEDLINE