Fibronectin is present on B-cells but not on OKT 3-positive T-lymphocytes or Leu 11-positive natural killer cells.

Autor: Klingemann HG, Ebert J, Deeg HJ
Jazyk: angličtina
Zdroj: Journal of leukocyte biology [J Leukoc Biol] 1986 Oct; Vol. 40 (4), pp. 491-5.
DOI: 10.1002/jlb.40.4.491
Abstrakt: We examined T-cells, B-cells, and natural killer cells of four normal individuals for surface-bound fibronectin (FN) using fluorescence-activated cell sorter analysis and double fluorescence labeling with monoclonal antibodies. While Leu 12 (CD 19)-positive B-cells stained also uniformly with anti-FN antibody, neither OKT 3 (CD 3)-positive T-cells nor Leu 11 (CD 16)-positive natural killer cells could be labeled with anti-FN. Although an anti-FN receptor antibody was not available, these data strongly suggest a distinct pattern of FN-binding by human lymphocytes.
Databáze: MEDLINE