High-resolution MRI data of the brain of C57BL/6J and BTBR mice in three anatomical views.

Autor: Ryabushkina YA; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Prospekt Lavrentyeva 10, Novosibirsk 630090, Russia., Shevelev OB; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Prospekt Lavrentyeva 10, Novosibirsk 630090, Russia., Kisaretova PE; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Prospekt Lavrentyeva 10, Novosibirsk 630090, Russia.; Novosibirsk State University, Pirogova Street 2, Novosibirsk 630090, Russia., Sozonov NG; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Prospekt Lavrentyeva 10, Novosibirsk 630090, Russia.; Novosibirsk State University, Pirogova Street 2, Novosibirsk 630090, Russia., Ayriyants KA; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Prospekt Lavrentyeva 10, Novosibirsk 630090, Russia., Bondar NP; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Prospekt Lavrentyeva 10, Novosibirsk 630090, Russia.; Novosibirsk State University, Pirogova Street 2, Novosibirsk 630090, Russia., Reshetnikov VV; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Prospekt Lavrentyeva 10, Novosibirsk 630090, Russia.; Sirius University of Science and Technology, 1 Olympic Avenue, Sochi 354340, Russia.
Jazyk: angličtina
Zdroj: Data in brief [Data Brief] 2021 Nov 20; Vol. 39, pp. 107619. Date of Electronic Publication: 2021 Nov 20 (Print Publication: 2021).
DOI: 10.1016/j.dib.2021.107619
Abstrakt: The research on strain-, sex-, and stress-specific differences in structural and functional connectivity of the brain is important for elucidating various behavioral features and etiologies of psychiatric disorders. Socially impaired BTBR mice are considered a model of autism spectrum disorders. Here we present high-resolution magnetic resonance imaging data from the brain of 89 adolescent mice (C57BL/6J and BTBR) in axial, sagittal, and coronal views. The study [1] includes both females and males differed in early-life experience (normally reared or subjected to prolonged maternal separation: 3 h daily from postnatal day 2 to 15). The MRI data were obtained on a horizontal tomograph Biospec 117/16 instrument with a magnetic field strength of 11.7 T. Thus, multislice Turbo RARE T 2 -weighted images of the brain were captured in eight groups of mice. Altogether, these data allow to evaluate strain-, sex-, and stress-specific alterations in the volumes of various brain structures and to better understand the relation between brain structural differences and behavioral abnormalities.
Competing Interests: None.
(© 2021 The Author(s). Published by Elsevier Inc.)
Databáze: MEDLINE
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