Risk Factors and Spatial Distribution of Schistosoma mansoni Infection among Preschool-Aged Children in Blapleu, Biankouma District, Western Côte d'Ivoire.

Autor: N'Zi CK; Institut National de Santé Publique, Abidjan BP V 46, Côte d'Ivoire., Ouattara M; Université Félix Houphouët-Boigny, 22 BP 582, Abidjan 22, Côte d'Ivoire.; Centre Suisse de Recherches Scientifiques en Côte D'Ivoire, 01 BP 1303, Abidjan, Côte d'Ivoire., Assaré RK; Université Félix Houphouët-Boigny, 22 BP 582, Abidjan 22, Côte d'Ivoire.; Centre Suisse de Recherches Scientifiques en Côte D'Ivoire, 01 BP 1303, Abidjan, Côte d'Ivoire.; Swiss Tropical and Public Health Institute, CH-4002, Basel, Switzerland.; University of Basel, CH-4003, Basel, Switzerland., Bassa FK; Université Félix Houphouët-Boigny, 22 BP 582, Abidjan 22, Côte d'Ivoire., Diakité NR; Université Félix Houphouët-Boigny, 22 BP 582, Abidjan 22, Côte d'Ivoire.; Centre Suisse de Recherches Scientifiques en Côte D'Ivoire, 01 BP 1303, Abidjan, Côte d'Ivoire., N'Goran EK; Université Félix Houphouët-Boigny, 22 BP 582, Abidjan 22, Côte d'Ivoire.; Centre Suisse de Recherches Scientifiques en Côte D'Ivoire, 01 BP 1303, Abidjan, Côte d'Ivoire.
Jazyk: angličtina
Zdroj: Journal of tropical medicine [J Trop Med] 2021 Nov 28; Vol. 2021, pp. 6224401. Date of Electronic Publication: 2021 Nov 28 (Print Publication: 2021).
DOI: 10.1155/2021/6224401
Abstrakt: Schistosoma mansoni infection is common among school-age children (SAC) in western Côte d'Ivoire. Little is known on the infection rate of preschool-aged children (PSAC) due to epidemiological data deficiency and nonappropriate formulation of the drug. Thus, mass drug administration for schistosomiasis control mainly targets SAC. This study aims to identify the risk factors and spatial distribution of S. mansoni infection among PSAC in Blapleu, endemic foci of S. mansoni . We carried out a cross-sectional study in households with PSAC aged 1-6 years. A structured questionnaire was administered to mothers/guardians to obtain data on sociodemographics and water contact behaviour of children. Point-of-care circulating cathodic antigen (POC-CCA) immunodiagnostic test in urine and Kato-Katz (K-K) method with stool were used for S. mansoni infection diagnosis. Multiple logistic regression analysis was performed to determine the relationship between S. mansoni infection and sociodemographic data. Coordinates recorded by a Global Positioning System of households, water source points, and infected PSAC were used to map the spatial distribution of S. mansoni infection cases. This study was conducted with 350 PSAC aged 1-6 years. The overall infection prevalence of S. mansoni varies from 31.43% with the K-K method to 62.86% with the POC-CCA. PSAC aged 2-6 years were highly infected with S. mansoni than those aged 1-2 years (OR = 14.24, 95% CI: 5.85-34.64). PSAC who did not have access and who do not live close to the infected water source were at a significant lower risk of S. mansoni infection (OR = 0.13, 95% CI: 0.057-0.30). The main purpose of water contact of PSAC was to help their mother for laundry that occurs weekly. In Blapleu, a high risk of S. mansoni infection was observed among PSAC. Schistosomiasis control effort in such localities should include information, education, and communication, water, sanitation, and hygiene, and particularly chemotherapy targeting PSAC, reinforcing the need of the paediatric praziquantel formulation.
Competing Interests: The authors declare no conflicts of interest regarding the published article.
(Copyright © 2021 Constant Konan N'Zi et al.)
Databáze: MEDLINE
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