18 F-Fluciclovine-Avid Axillary Lymph Nodes After COVID-19 Vaccination on PET/CT for Suspected Recurrence of Prostate Cancer.

Autor: Peacock JG; Department of Radiology, Uniformed Services University, Bethesda, Maryland.; Department of Radiology, San Antonio Military Medical Center, San Antonio, Texas; and., Banks EA; College of Natural Sciences, University of Texas at Austin, Austin, Texas libbybanks@utexas.edu., McWhorter N; Department of Radiology, Uniformed Services University, Bethesda, Maryland.; Department of Radiology, San Antonio Military Medical Center, San Antonio, Texas; and.
Jazyk: angličtina
Zdroj: Journal of nuclear medicine technology [J Nucl Med Technol] 2022 Mar; Vol. 50 (1), pp. 73-74. Date of Electronic Publication: 2021 Dec 06.
DOI: 10.2967/jnmt.121.263001
Abstrakt: Abnormally increased 18 F-FDG avidity of axillary lymph nodes has become a frequent diagnostic dilemma on PET/CT in the current climate of global vaccinations directed against severe acute respiratory syndrome coronavirus 2. This avidity is due to the inflammatory response evoked by vaccines and the nonspecific nature of 18 F-FDG uptake, which is increased in both malignant and inflammatory processes. Similarly, 18 F-fluciclovine, an amino acid analog indicated for the assessment of biochemical recurrence of prostate cancer, may also demonstrate nonspecific inflammatory uptake. We report a case of 18 F-fluciclovine PET/CT obtained for concern about prostate cancer. In this case, isolated avid lymph nodes were seen in the left axilla. A screening questionnaire revealed that the patient had recently received the second dose of the Pfizer-BioNTech coronavirus disease 2019 vaccine in his left shoulder, and hence, the uptake was determined to be reactive.
(© 2022 by the Society of Nuclear Medicine and Molecular Imaging.)
Databáze: MEDLINE