Adherence to the EAT-Lancet Diet and Risk of Stroke and Stroke Subtypes: A Cohort Study.

Autor:	Ibsen DB; Department of Public Health (D.B.I., A.H.C., A.O., K.O., C.C.D.), Aarhus University, Denmark.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (D.B.I., A.W.)., Christiansen AH; Department of Public Health (D.B.I., A.H.C., A.O., K.O., C.C.D.), Aarhus University, Denmark., Olsen A; Department of Public Health (D.B.I., A.H.C., A.O., K.O., C.C.D.), Aarhus University, Denmark.; Danish Cancer Society Research Center, Copenhagen, Denmark (A.O., A.T.)., Tjønneland A; Danish Cancer Society Research Center, Copenhagen, Denmark (A.O., A.T.).; Department of Public Health, University of Copenhagen, Denmark (A.T.)., Overvad K; Department of Public Health (D.B.I., A.H.C., A.O., K.O., C.C.D.), Aarhus University, Denmark., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (D.B.I., A.W.)., Mortensen JK; Department of Clinical Medicine (J.K.M.), Aarhus University, Denmark.; Department of Neurology, Aarhus University Hospital, Denmark (J.K.M.)., Dahm CC; Department of Public Health (D.B.I., A.H.C., A.O., K.O., C.C.D.), Aarhus University, Denmark.
Jazyk:	angličtina
Zdroj:	Stroke [Stroke] 2022 Jan; Vol. 53 (1), pp. 154-163. Date of Electronic Publication: 2021 Dec 07.
DOI:	10.1161/STROKEAHA.121.036738
Abstrakt:	Background and Purpose: We investigated the association between adherence to the EAT-Lancet diet, a sustainable and mostly plant-based diet, and risk of stroke and subtypes of stroke in a Danish population. For comparison, we also investigated the Alternate Healthy Eating Index-2010 (AHEI). Methods: We used the Danish Diet, Cancer and Health cohort (n=55 016) including adults aged 50 to 64 years at baseline (1993-1997). A food frequency questionnaire was used to assess dietary intake and group participants according to adherence to the diets. Stroke cases were identified using a national registry and subsequently validated by review of medical records (n=2253). Cox proportional hazards models were used to estimate hazard ratios and 95% CIs for associations with the EAT-Lancet diet or the AHEI and risk of stroke and stroke subtypes. Results: Adherence to the EAT-Lancet diet was associated with a lower risk of stroke, although not statistically significant (highest versus lowest adherence: hazard ratio, 0.91 [95% CI, 0.76-1.09]). A lower risk was observed for AHEI (0.75 [95% CI, 0.64-0.87]). For stroke subtypes, we found that adherence to the EAT-Lancet diet was associated with a lower risk of subarachnoid hemorrhage (0.30 [95% CI, 0.12-0.73]), and the AHEI was associated with a lower risk of ischemic stroke (0.76 [95% CI, 0.64-0.90]) and intracerebral hemorrhage (0.58 [95% CI, 0.36-0.93]). Conclusions: Adherence to the EAT-Lancet diet in midlife was associated with a lower risk of subarachnoid stroke, and the AHEI was associated with a lower risk of total stroke, mainly ischemic stroke and intracerebral hemorrhage.
Databáze:	MEDLINE
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