Association of Overweight and Consistent Anovulation among Infertile Women with Regular Menstrual Cycle: A Case-control Study.
| Autor: | Giviziez CR; Unidade Acadêmica de Ciências da Saúde, Universidade Federal de Jataí, Jataí, GO, Brazil., Sanchez EGM; Unidade Acadêmica de Ciências da Saúde, Universidade Federal de Jataí, Jataí, GO, Brazil., Lima YAR; Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Hospital das Clínicas, Laboratório de Reprodução Humana, Universidade Federal de Goiás, Goiânia, GO, Brazil., Approbato MS; Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Hospital das Clínicas, Laboratório de Reprodução Humana, Universidade Federal de Goiás, Goiânia, GO, Brazil. |
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| Jazyk: | angličtina |
| Zdroj: | Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia [Rev Bras Ginecol Obstet] 2021 Nov; Vol. 43 (11), pp. 834-839. Date of Electronic Publication: 2021 Dec 06. |
| DOI: | 10.1055/s-0041-1739464 |
| Abstrakt: | Objective: It has been suggested that excess body weight could represent a risk factor for infertility outcomes. The present study aimed to evaluate the association of overweight and anovulation among infertile women with regular menstrual cycles. Methods: We conducted a retrospective case-control study with consistently anovulatory patients undergoing assisted reproduction treatment. The patients were stratified into normal weight (body mass index [BMI]: 18.5-24.9kg/m 2 ) and overweight (BMI: 25.0-29.9kg/m 2 ).Those with polycystic ovary syndrome or obesity were excluded. The groups were matched for age, duration of infertility, prolactin, follicle stimulating hormone (FSH), thydroid stimulating hormone (TSH), luteinizing hormone (LH), and estradiol levels. Results: Overweight was significantly associated with anovulation, when using the World Health Organization (WHO) criteria for anovulation: progesterone levels > 5.65 ng/ml and ultrasonography evidence of follicle collapse (odds ratio [OR]: 2.69; 95% confidence interval [CI95%]: 1.04-6.98). Conclusion: Body mass index above the normal range jeopardizes ovulation among non-obese infertile women with regular menstrual cycles. Competing Interests: The authors have no conflict of interests to declare. (Federação Brasileira de Ginecologia e Obstetrícia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).) |
| Databáze: | MEDLINE |
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